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Cort Rx – Strategies for use

Cort rx

Cort Rx is a combination of herbs that help the body to deal with stress. They help the body to return to normal after stress regardless of the direction of change. This means when up and anxious they will calm you down but when down and fatigued they will help to pick you up. They achieve this by working directly with the HPA axis and adrenal gland to help regulate the stress response and have a sparing effect on the adrenals. They also work by reducing stress on the body form inflammation, immune dysfunction, oxidative stress, and toxic exposure with anti-inflammatory, antioxidant, immune-modulating and liver-protective herbs.

How do I use Cort Rx?

There are many ways to use Cort Rx and there are a variety of different dosing strategies for this. Cort Rx can be used for acute short-term intense aggressive protocols for inflammation, toxicity, immune challenge or stress; and Cort Rx can be used to address long term chronic issues such as adrenal maladaptation.

How should I feel on Cort Rx?

Well, that depends on you. We are all individuals and may react differently to herbal ingredients due to genetic variances in pharmacodynamics. It also depends on what stage of HPA dysfunction you are in and what other changes you have made.

The brain picks up on stress triggers and sends a message to the adrenal gland to launch a stress response. There are 2 parts to the adrenal gland. 1. The nervous part (the adrenal medulla) that triggers our nervous response to stress to keep us alert and awake. 2. The hormonal part (adrenal cortex) and that releases hormones to switch off our nervous response to stress, regulates our sleep and wake cycles and creates other hormones for recovery and repair.

Typically we never exhaust the nervous response to stress but the adrenal cortex can lose its ability to regulate the nervous response to stress and switch off the stress axis and stress triggers. So it is the adrenal cortex we need to treat to help restore adrenal function and provide balance.

How do Adaptogens Work?

It is important to understand how “adaptogens” work. Adaptogens help you to adapt to stress regardless of the direction of change. This means they will try to drag you back to the middle and away from extremes.

Adaptogens work by

  • – Reducing stress signals in the first place to take the burden off the adrenals.
  • – Regulating the nervous response to stress. If down they will pick you up but if the nervous part is too intense they will slow it down.
  • – Supporting the adrenal cortex to restore hormonal balance

This means they will keep you in the middle ground and away from the extreme buzz associated with anxiety and panic by reducing your stress response to stimulants, pain, inflammation, worry, and fear.

If you are running on nervous energy and the only thing keeping you on the go is stress, stimulants, anxiety, nerves, and worry, etc.  Then adaptogens will force you to slow down and give a chance for you and your adrenal cortex to recover.

If you combine adaptogens with stimulants they will reduce the degree of stimulation and keep you in a safer zone.

If you suddenly stop stimulants, caffeine, toxicity, etc. and use adaptogens you may go through a phase of conservation while restoring adrenal cortex integrity before you really feel the next level improvements.

Perhaps you are in the early phases of adrenal hyper-reactivity they will reduce the nervous energy and make your energy usage more efficient with improved sleep-wake cycles. Wide awake all day and nice deep sleep at night.

Later Stages of Exhaustion

If you are in the later stages of adrenal exhaustion than it will actually help to reduce the nervous energy while restoring the adrenal cortex hormonal control. Once the adrenal cortex is working you will have an abundance of energy during the day and deep refreshing sleep at night but in the very short term you may feel more fatigued without the nervous energy and taking adaptogens during the day may make you feel tired and in this case just use at night to enhance deep refreshing sleep and allow the adrenal to work all day and rest at night.

Chronic protocols

Which stage of adrenal dysfunction are you?


Cortisol secretion in the morning blocks sleep chemicals to wake you up so you couldn’t possibly roll over and go back to sleep now that you are awake; while inhibiting inflammation relieving aches and pains, sinus, hay fever and rashes. As evening comes, cortisol drops dramatically and sleep chemicals rise so you are forced into a nice deep sleep. While sleeping cortisol drops extremely low and the immune system and other regenerative and anabolic systems fire up to grow, repair and generally clean up.

Cort RX – 1 capsule 3 times daily with meals.


Acute stress (figure 2.)

Cortisol spikes when needed through the day to help overcome stressors before returning to normal.

Cort Rx – take 1 capsule 3 times daily with meals

Cort rx stress

Chronic stress (figure 3.)

Exaggerated and prolonged cortisol spike. Start waking up with high cortisol and it spikes from there and never really drops enough all day and night for chronic elevated cortisol exposure. Nervous energy all day and restless, unrefreshing, light sleep.

Cort Rx – take 1 capsule 3 times daily with meals.

Cort rx chronic stress

Hyper-reactive (figure 4.)

Born pre-wired, acquired acute (PTSD) or chronic stress. Fibromyalgia, Insomnia, depression borne from anxiety. Due to cortisol resistance you have learnt to release extra cortisol in response to stress and subsequently an exaggerated stress response. Referred to as melancholic depression in literature and responds to serotonin preserving antidepressants

Constant excessive exposure leads to cortisol resistance and low levels now fail to register so the body pumps out more and more. This causes a vicious cycle that results in a phase of conservation or adrenal fatigue.

Cort Rx – take 1 capsule 3 times daily

cort rx hyper reactive

Conservation (figure 5.)

Fibromyalgia / Chronic fatigue syndrome, shift workers, mums, acquired by progressing through the stages of HPA maladaptation. Auto-immune, excessive inflammation, allergies, fatigue and pain.

Not enough to get up and going but too much to get a good night’s sleep. Light sleep and seem more awake before bed then when you rose. Wake unrefreshed. Need stimulants to get going and only temporary. Usually sensitive to glare, thirsty all the time but can’t hold water so need to urinate constantly, crave salt and / or sugars

Wakes with pain that gradually leaves

Chronic inflammation leads to all age related disorders

The conservation phase can also manifest as bizarre cortisol patterns that reflect poor sleeping patterns and adaptations to lifestyle in shift workers, mums, and hospitality and security workers.

Cort Rx – take 2 capsules with evening meal and another 2 capsules before bed. Drop dose to 2 capsules with evening meal as a maintenance dose after 1 week.


cort rx conservation

Hypo reactive (adrenal fatigue) (figure 6.)

Born congenital defect, autoimmune, exhaustion, Chronic Fatigue Syndrome. Hypersomnia, pain, inflammation, depression borne from apathy and fatigue with low cortisol and excessive serotonin activity. Referred to as atypical depression in literature and doesn’t respond to serotonin preserving antidepressants well.

Cort Rx – take 2 capsules with evening meal and 2 capsules before bed.

cort rx hypo reactive

The reality is that most of us are actually living in the conservation phase and using stimulants and sedatives to influence us into hyper-reactive, push on and work, or hypo-reactive, to crash and sleep. You may also notice how easy it may be for someone to hover between different types of depression and ultimately style of treatment. Adjust dosing strategies as you move through the stages on your journey to good health “normal”.

Acute protocols

Anti-inflammatory – Pain, injury, bruising, trauma, DOMS, Auto-immune

Take 2 capsules 3 to 6 times daily for 72 hours and then reduce dose to 1 capsule 3 to 6 times daily for next 48 hours and then drop to 1 capsule 3 times daily once acute pain and inflammation has reduced.

Toxicity – toxic exposure, alcohol, recreational drugs, hangover etc.

Take 2 capsules 3 times daily with meals and another 2 capsules before bed. You may maintain this dose for 2 to 4 weeks before reducing to 1 capsule 3 times daily as a maintenance dose.

Infection – colds / flus, trauma sites

Take 2 capsules 4 times daily for 3 days and then reduce to 1 capsule 4 times daily for next 3 days and then reduce to 1 capsule twice daily with meals as a maintenance dose.

Allergy – hay fever, sinus, rashes, itchy eyes, membranes and skin.

(Not suitable if allergic to Cort Rx ingredients)

Take 2 capsules 4 times daily

Insomnia – poor onset and / or poor sleep maintenance and / or poor sleep quality

Take 2 capsules with evening meal and another 2 capsules before bed. Reduce the dose to 2 capsules after a few days for a maintenance dose.


9 replies to “Cort Rx – Strategies for use”

  1. Hi guys i just brought Cort RX to use for an Anti-inflammatory purpose as train with heavy weights and am always getting very minor injuries like pulled muscles & strains. But taking them during the day makes me sleepy. I still drink coffee but only for the taste as caffeine doesn’t seem to affect me Should i just ride it out and will it get better? Or my friend told me to take 2 with dinner and 2 before i go to bed. I also take Venus and just got the prototype. Should I use the prototype as well on my injuries?

    1. Hi Ayla,

      Yes try taking it just at night with dinner and before bed, people are either sensitive to it during the day or they aren’t. Prototype 8 is great on injuries after the acute inflammation has gone down :-)

    2. I too found that the Cort RX was making me tired in the arfternoon, to the point I was almost dosing off. After reading this article on Cort RX, I will now take two at dinner and then two before bed. Awesome read and thanks for the great in depth article on how to understand the products you develop. Light years ahead of any other supplement company.

  2. Hi Elsa,
    I was taking cortRX to assist with my adrenal fatigue, stress and anxiety, to help me sleep. I was taking two at night for about 3 months and it worked great with my sleep. I have stopped taking it and now I am sleeping well without it, but experiencing nervous energy/stress/anxiety during the day. Would you recommend that I now just take it during the day? and at what dosage? Thanks!

    1. Hi Sara,

      Great to hear you are sleeping well again after the Cort RX, yes so I would just recommend either taking a capsule when you are feeling anxious or overly stressed or you can just take a standard dose of x1 cap with breakfast and x1 cap with lunch just so you can get a steady dose through the day :-)

  3. hey! just read on the insomnia how long before sleeping would you recommend taking the 2 capsules for anxiety before bed/not getting to sleep?

  4. Hey guys, I’m a 27yo female & I’ve been using Cort Rx for 2 weeks now – 2 tablets with dinner and haven’t noticed a change in my sleep patterns. I don’t struggle getting to sleep (probably takes around 10 minutes at most), but I struggle with deep sleep (according to my Fitbit I’m getting anywhere from 20 minutes to max an hour and a half deep sleep) but whenever I wake up I could easily go back to sleep again – it takes about 4 alarms to get me up. I’m in bed around 930-10 and my first alarm goes off at 5:25am for my gym session. I eat well, train hard, work 830-530 and definitely experience stress throughout my day. I’m wondering if I should trial taking 1 tablet 3 x daily with food (I’ve actually tried that today and have felt more tired than ever this afternoon but appreciate it takes time). My biggest concern is that my bad gut health means I’m not able to absorb the nutrients as my body requires.

    Would appreciate any guidance!

    1. Hi Soph,
      Great question and I would definitely recommend trying 1 capsule 3 times per day to see if that helps, keep us updated on how you go :-)


  5. this product is great for stress and my anxiety.. ashame its 4 times the price of my previous anti depressant medication :(

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