Product Description
CortRX
CortRX is a product that contains Schisandra, Turmeric, Rhodiola, and Withania.
CortRX is a powerful combination of adaptogenic herbs; adaptogens help you deal with stress and adapt to the situation at hand via helping support the normal function and efficiency of our stress axis.[i] *
If we’re getting chased by a tiger; massive amounts of adrenalin and cortisol would have been released by the body so we could (hopefully) outrun or outfight the beast. If we didn’t have that response, we would have been the big cat’s lunch; and of course, then not had a chance to make babies. This is partly why there are so many people suffering from stress in the world. You inherited a survival technique that is ideal for surviving acute life-threatening stress but may not be the most efficient way to deal with an internet troll, a bully, a text, bills, public speaking, crowds, or that boss on your back.
How we react to stress
Nowadays, most of us aren’t being chased by big cats but our genes are still programmed that way. The ‘beast’ chasing us today is chronic stress, the long-term daily grind, and constant exposure and unavoidable stress unlike the Tiger’s ‘minutes’ of acute intense stress.
Each time, regardless of the trigger we release neurotransmitters (such as noradrenaline) and hormones (in particular cortisol) that catalyze a series of events that help us deal with the challenge. Cortisol is a very interesting hormone as it helps with the survival response through various mechanisms like increasing blood sugar[ii] and blocking relaxation and sleepy chemicals (serotonin)[iii] but then it has a “negative feedback” effect, letting the body know that you had a stress response and can now switch off and relax.
The problem is with modern life there is constantly one form of trigger or another so there is a constant stimulus to pump out these stress chemicals. Chronic exposure to powerful hormone-like cortisol can increase fat gain, disrupt healthy sleep patterns, immune responses, fluid distribution, and blood sugar. [iv]
Yet here we are with the mortgage, stressful job and even environmental stress we simply can’t escape. We just have to manage these unavoidable stressors better.
The hormonal fluctuations
To fully understand how to influence hormonal secretions and activities we must first understand the big picture and know the natural cycles that dictate our body’s priorities between thriving or surviving. The Hypothalamus in our brain collects data from our body to inform of potential stressors.[v] Our body can’t afford to wait and see if something is life-threatening before it reacts, therefore it will trigger a stress response, proactively, just in case. The immune system, inflammatory chemicals, emotional stress, fear, pain, temperature extremes, toxicity, training hard, caffeine, etc. will all activate the Hypothalamus to initiate a survival response. The end result is that the hypothalamus sends this stress message to our pituitary gland, which then signals the adrenals to pump out cortisol.[vi] This, of course, is a natural response but too much cortisol is very bad for our health.[vii][viii][ix][x][xi][xii][xiii][xiv]
How do I take Cort RX?
Cort Rx is formulated to help you maintain a healthy stress response.
If you are going through a stressful period with busy days that are leaving you feeling “wired but tired” and unable to switch off; you can take Cort Rx 1 capsule 3 times daily with food.
If you find that the more tired you get the harder it is to get a good night’s sleep than take 2 Cort RX before bed.
Most people may find they hover between these two phases going from an overflowing cup to empty. Cort Rx can help and you can change the way you take it to suit your current lifestyle.
Take-Home Message
If you feel you have cortisol dysregulation, try to reduce the stressors in your life. Seek help from medical professionals and discuss Cort Rx as an optional tool to help with your holistic lifestyle strategy.

References
[i] Exp Ther Med. 2016 Jan; 11(1): 353–359. Published online 2015 Nov 19. doi: 10.3892/etm.2015.2882
Schisandra chinensis and Rhodiola rosea exert an anti-stress effect on the HPA axis and reduce hypothalamic c-Fos expression in rats subjected to repeated stress. NAN XIA,1 JIE LI,1 HONGWEI WANG,2 JIAN WANG,1 and YANGTIAN WANG1
[ii] Clin Sci (Lond). 2001 Dec;101(6):739-47. Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome. Khani S1, Tayek JA.
[iii] Cogn Affect Behav Neurosci. 2001 Dec;1(4):388-93. Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. Tafet GE1, Idoyaga-Vargas VP, Abulafia DP, Calandria JM, Roffman SS, Chiovetta A, Shinitzky M.
[iv] Domest Anim Endocrinol. 2016 Jul;56 Suppl:S112-20. doi: 10.1016/j.domaniend.2016.03.004. Epub 2016 Mar 31. Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity.
Hewagalamulage SD1, Lee TK1, Clarke IJ1, Henry BA2.
[v] Compr Physiol. 2015 Jan;5(1):217-53. doi: 10.1002/cphy.c140019. Hypothalamus as an endocrine organ.
Clarke IJ1.
[vi] Compr Physiol. 2016; 6(2): 603–621. Published online 2016 Mar 15. doi: 10.1002/cphy.c150015
Regulation of the hypothalamic-pituitary-adrenocortical stress response James P. Herman, Jessica M. McKlveen, Sriparna Ghosal, Brittany Kopp, Aynara Wulsin, Ryan Makinson, Jessie Scheimann, and Brent Myers
[vii] Domest Anim Endocrinol. 2016 Jul;56 Suppl:S112-20. doi: 10.1016/j.domaniend.2016.03.004. Epub 2016 Mar 31. Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity.
Hewagalamulage SD1, Lee TK1, Clarke IJ1, Henry BA2.
[viii] Clin Sci (Lond). 2001 Dec;101(6):739-47. Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome. Khani S1, Tayek JA.
[ix] MAYER EA The neurobiology of stress and gastrointestinal disease Gut 2000;47:861-869.
[x] MAYER EA The neurobiology of stress and gastrointestinal disease Gut 2000;47:861-869.
[xi] MAYER EA The neurobiology of stress and gastrointestinal disease Gut 2000;47:861-869.
[xii] Cogn Affect Behav Neurosci. 2001 Dec;1(4):388-93. Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. Tafet GE1, Idoyaga-Vargas VP, Abulafia DP, Calandria JM, Roffman SS, Chiovetta A, Shinitzky M.
[xiii] Steroids. 1995 Jan;60(1):76-80. Mechanisms of cortisol-induced hypertension in humans. Whitworth JA1, Brown MA, Kelly JJ, Williamson PM.
[xiv] Domest Anim Endocrinol. 2016 Jul;56 Suppl:S112-20. doi: 10.1016/j.domaniend.2016.03.004. Epub 2016 Mar 31. Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity.
Hewagalamulage SD1, Lee TK1, Clarke IJ1, Henry BA2.
United States of America Orders
ATP Science offers a flat rate standard shipping option, express shipping and free standard shipping on orders over $150.00 USD to all US customers. We use a 3rd party logistics company in the US (Texas) to ship all of our orders so they will come from within the US. Shipping prices are below for the US:
Flat rate shipping (3-8 Working days): $9.95 USD
Express shipping (2-5 Working days): $14.95
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ATP Science aims to get all orders dispatched within 1-2 business days of you placing your order. ATP Science do not ship orders on public holidays and/or weekends.
ATP Science does not take responsibility of any delays of your parcel/order from the moment it is handed to the courier driver.
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- Express Shipping (1-5 Working Days): $15.00
- Free Standard Shipping on all orders over $150.00
Tracking Your Order:
Australia Post: www.auspost.com.au/track/track.html
ATP Science aims to get all orders dispatched within 1-2 business days of you placing your order. ATP Science do not ship orders on public holidays and/or weekends.
ATP Science does not take responsibility for any delays of your parcel/order from the moment it is handed to the courier driver.
ATP Science aims to get all orders dispatched within 1-2 business days of you placing your order. ATP Science does not ship orders on public holidays and/or weekends.
ATP Science does not take responsibility for any delays of your parcel/order from the moment it is handed to the courier driver.
Orders from International Customers (excluding USA)
ATP Science offers a flat rate standard shipping option to all International customers. We use Australia Post and DHL for all of our parcels shipped overseas (excluding USA).
Flat rate shipping (3-7 Working Days): $9.95 USD.
Track your Order:
Australia Post: www.auspost.com.au/track/track.html
DHL: http://www.dhl.com.au/en/express/tracking.html
ATP Science aims to get all orders dispatched within 1-2 business days of you placing your order. ATP Science does not ship orders on public holidays and/or weekends.
ATP Science does not take responsibility for any delays of your parcel/order from the moment it is handed to the courier driver.
International Customers Please Read the Below (Especially UK customers)
Import taxes: You may have to pay import taxes and/or customs duties. You may also be required to pay a brokerage (handling) fee for the shipment. These charges are separate from your shipping charge and you will be billed directly for them via the shipping carrier. These shipping and tax rates vary from country to country and also depend upon the products being ordered. ATP Science has no control over these charges.
Declaration of Value and Product Description: International shipments are processed with a commercial invoice as required to ship internationally. Customs may make additional requests based on local laws and regulations. Due to the complexity of some requests, we cannot guarantee that the additional information requested will be provided. The requests may differ depending on the order value, regulations, and other unpredictable factors.
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Address or other customer error: If a package is returned to ATP Science due to an address error (or any other error) made by the customer, the customer will be responsible for any shipping fees incurred. A refund will be issued for merchandise only, minus a 10% restocking fee*, upon receipt of the returned package. This also applies to customer refusal of a package (in which the customer will have the cost of the return shipment taken from the total refund).
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We request that you contact your customs office and ask about import regulations and restrictions before placing your order. It is important for you to become familiar with Customs policies for your specific country before ordering.
Customs regulations differ by country and not knowing their regulations can result in your order incurring high import duties, the delivery being delayed or even returned. Please check with your Customs office to see if your country permits the shipment of the products you are planning to order from us and if any additional licenses or permits are needed.