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Gut Health and Obesity

Our gut health can significantly alter the energy in: out ratios and contribute to obesity.

There is so much research going into genetic links to obesity. The new research suggests that our genetic polymorphisms (polymorphism is a variation of a gene. Not a defect but a variant) alone DO NOT EXPLAIN the obesity epidemic.

Which to me makes sense considering our genes have not had enough time to change dramatically enough over the short time period of the obesity epidemic has occurred yet other environmental factors and mutations and evolution of the genetic code of microbes have changed dramatically in this time period. Microbes are capable of mutating within minutes for survival and reproduction. A new strain of flu hits every year, a mutated and evolved form of last year’s bugs.

Your gut microbiome is made up of 500–1000 species and the genetic potential of this load of bugs living inside you can exceed 100 fold the number of human genes you have controlling your metabolism now. Many of these bacterial genes have unique functions that can directly affect our metabolism and can either help us hurt us.

Until recently scientists have not been able to study the gut microbiota, as many of these organisms cannot be grown in culture or identified, thereby limiting our ability to investigate their individual physiological and metabolic roles. New metagenomic technology now allows us to study the microbiota.

The common pattern in gut flora in obesity is;

(1) an increased ratio of Gram-positive bacteria to Gram-negative bacteria,

(2) an increased abundance of the obesogenic microbiota Firmicutes and a decreased abundance of the lean microbiota Bacteroidetes,

(3) excessive amounts of the firmicute bacteria Lactobacillus

Obese humans have too many firmicutes

The gut microbiota is associated with and can now be used to predict obesity in humans and in animal models. When the abundance of Bacteroidetes decreases there is a proportional increase in the Firmicutes in obesity. Those with obesity or potential for obesity seem to accumulate and propagate firmicutes easily.

Obesity itself can change the gut flora independently of diet changes and changing gut flora to obesogenic profile can create obesity.

This means that somehow the changing body composition, changing hormonal profile, potential for insulin resistance and fatty liver etc. can change the gut flora to create a vicious cycle that is not simply fixed by changing macro nutrient profile.

If you are one of those people that can do the diet and exercise that works for everyone else, you have your maths right and calories in and out calculated correctly and still do not see change; then you may need to make significant changes to your gut flora at the same time to break the vicious cycle.

Why is this happening?

  • Firmicutes feed on sugar
  • They make u crave sugar
  • They create insulin resistance to keep sugar available for themselves
  • They create space for themselves by poisoning off competition by destroying their ability to burn sugar for fuel (we get that toxin in us too)
  • They convert sugar to acid to kill of other bugs that can’t handle acid
  • Firmicutes are more effective at promoting efficient absorption of calories as an energy source than Bacteroidetes.
  • Firmicutes alter serotonergic function by taking tryptophan away from serotonin and takes it down a pathway that makes nerve irritants and kerb cycle modifiers instead. This creates cravings, fatigue, obesity and depression / anxiety.

The end result is you are stuck in a vicious cycle

  • Inflammation and inflammatory triggers,
  • The wrong types of acid and short chain fatty acids,
  • Toxins that disturb your kreb cycle that create obesity.
  • And vice versa, obesity creates insulin resistance and inflammation, lack of exercise and higher blood sugar that creates the altered gut microbiome

Break the vicious cycle


And take 1 teaspoon 3 x daily for 10 days to reduce microbial load while following the specific carb diet plan //

And then drop back to 1 teaspoon daily after that to maintain good gut health and follow the Modbiotic ™ diet plan long term to maintain. Get Your GutRight