Menopause, Andropause and SERMS Transcript
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ATP Science Episode 30 – Menopause, Andropause and SERMS
Welcome to the ATP Project, Episode 30 – Menopause, Andropause and SERMS.
Matt and I discuss the impact of natural loss of Testosterone in both men and women as we age, and just how important the Adrenal Function is for Hormone Production.
• Affects for both Men and Women.
• Importance of Adrenal Function for Hormone Production.
• A breakthrough in Selective Estrogen Receptor Modifiers, SERMS.
• Effectiveness of SERMS in Building Muscle.
• SERMS as a secret weapon for women.
• FAQs. Including one on Post Menopause and Disease
Welcome to the ATP Project, you’re with your hosts Matt and Jeff.
Jeff: Now, we did one a while back, I think it was one of the first Episodes that we’ve done, but I wanted to cover a bit more ground in today’s episode. I want to talk about Menopause, Andropause, Sex Hormone Binding Globulin, Free Testosterone, Steroids, DHT, all this sort of stuff.
Jeff: There’s a bit to cover, and it is such a massive topic so we’re probably not going to be able to cover absolutely everything, but let’s just cover as much as we can.
Jeff: Matt, Testosterone?
Jeff: What do you want to talk about, mate?
Matt: People know the basics. It’s good for a lot of things, Testosterone helps to build Muscle, helps to build Bone, Anti-Inflammatory, helps to regulate the Immune System, massive effects on the Brain, Motivation and Drive and Vitality, Virility, Sperm, Caveman stuff, you know.
Jeff: And, for women?
Matt: For men and for women. The sperm not so much for the women. Well—they won’t make sperm no.
Jeff: No. And, we’re going to get onto the athletes Hypertrophy, Muscle Growth. We understand that athletes want it, they need it, faster, fitter, stronger, all that sort of stuff. For non-athletes, Matt, Andropause—so, for the guys who are going through that—and, this is something that really…
Matt: That’s for everyone.
Jeff: Andropause, we haven’t spoken a lot about that, and not many people speak about it.
Matt: We better tell them what it is.
Jeff: Well Matt, Andropause?
Matt: The male Menopause.
Jeff: Right. So, what is that exactly? Break it down.
Matt: Well, basically, for both men and women, from mid-thirties onwards your Gonadal production of Hormones will start to decline. So, in the men the Testes and in the women the Ovaries will stop making as much Hormone and then the Adrenal Gland has to compensate and make a bit of extra Hormone to make sure you’ve got adequate Hormones for Maintenance and Repair as well as short term Survival. So, Testosterone is very important for Maintenance and Repair, Regeneration, our ability to heal injuries. After we breakdown Muscle it’s got the ability to grow that Muscle back and more under the right circumstances, and Testosterone is very important for all of those things. As with anything, too much or too little is bad.
So, typically, what happens around Andropause and Menopause there is a decline in Androgens as well as Estrogens.
Jeff: And, typically, what age is that, Matt? I know it can change depending on the individual.
Matt: Mid-thirties, typically. From mid-thirties onwards it’s starting to significantly decline. I mean mid-twenties you’ll peak with your Testosterone production and that sort of stuff, and it will decline from there, but from the mid-thirties the Testes in men they’re really starting to slow down with their Testosterone production, and the Adrenal Gland has to make a little bit more.
Jeff: And, so that I understand—I understand that Luteinising Hormone is produced, that then sends a signal to the Testes to produce Testosterone. How does it work in women? Where do women produce Testosterone? Is it all through the Adrenals?
Matt: When they’re getting a Menstrual Cycle the first half of the Menstrual Cycle is called the Follicular Phase, and that’s when they have Follicle Stimulating Hormone, and it’s telling the Ovaries to mature a Follicle, and it does that by converting the Testosterone that’s already in the Ovaries into Estrogen and that feeds the Follicle to develop. Then, once the little egg, or the Follicle pops off there’s a little sack that’s left over and it starts making Progesterone, which is also an Androgen. So, you’ll find in women the Testosterone production is supposed to be relatively consistent, so they’re supposed to be making a certain amount of Testosterone throughout the month to maintain Muscle Mass and all that sort of stuff. But, in regards to Estrogen and Progesterone the first half of the cycle is usually dominated by Estrogen, and then that’s the part of the Menstrual Cycle that builds all the period, changes the boobs, gets everything ready. Then, the egg pops off, Progesterone comes out, which gets its name from Pro-Gestation, because it’s your pregnancy Hormone, and it says, “Hold the egg there, hold all that period in and wait a couple of weeks to see if a sperm arrives.”
Then, what happens, if no fertilisation occurs the Hormones drop and then they have period. Once the egg’s run out that’s the bit—so, it’s when we’re running out of eggs and that sort of stuff that your Menstrual Cycle can be a bit hit and miss, and the body then would use the Adrenal Gland to increase Hormonal production to compensate.
The weird things is, what typically happens first, and this is in women, because Ovulation will often be the problem. So, they’re often making enough Estrogen, because you can make Estrogen out of fat cells and all that, so they’re making enough Estrogen and that stuff to make a period and everything, but they don’t necessarily Ovulate, which means they don’t get the surge of Progesterone, which means they don’t get that Hormone that’s released saying, “Stop making period, or hold it in.” So, a sign for a woman who’s coming into Menopause is that she might have a show when she’d normally be Ovulating, with a bit of spotting or bleeding, or start getting periods every couple of weeks, or miss a period for a long period of time. So, they start to go through a phase where they’re Hormones are a little bit weird, and at that time the Adrenal Gland is supposed to be making extra Hormone to compensate for that deficiency.
The problem is, the Adrenal Gland, well the Adrenal Cortex, the outside of the Adrenal Gland, that’s what makes these Hormones, and it makes them out of Cholesterol. So, one building block goes to this part of the Adrenal Gland, and the Adrenal Glands has to use this Cholesterol to make Cortisol for Short Term Survival, or make things like, Pregnenolone, DHEA, Progesterone, Testosterone, Estrogen. So, your Adrenal Gland, not only is it—you’ve got to realise with the Ovaries and that they’re only making those Hormones, Reproductive Hormones, the Regeneration and Repair ones.
But, your Adrenal Glands their main priority is Short Term Survival.
Matt: So, if your Adrenal Gland is struggling to just deal with Inflammation, Stress, Toxic Exposure and all that stuff, if it’s struggling to use all of its resources to make adequate Cortisol to keep you going and it doesn’t have enough resources left, or it doesn’t believe it’s important enough to worry about Maintenance and Repair if you’re not going to survive the day, so all of a sudden the Adrenal Gland gets all this extra burden and it’s trying to decide what’s most important, Short Term Survival and making Cortisol or long term happiness to make these other Reproductive, Regenerative, Reparative Hormones.
Jeff: So, from what you’re saying, if I’m correct, the importance of looking after the Adrenals for someone who’s Menopausal or Post-Menopausal is probably—we shouldn’t say of more importance but it’s critical.
Matt: Well, it’s inevitable that the Ovaries are going to stop.
Jeff: Yeah, that’s right.
Matt: And, a lot of women when they start getting these really weird bleeding and everything like that, their Androgens drop before the Estrogen and so they’re making all this period but they don’t have the Androgens to hold it in, so the get all this bleeding. Then, they go get it checked, and because they’ve got Estrogen Dominance around that same time—because, they can start getting abnormal cells showing up, and often they’ll get a Hysterectomy and then they’ll do a token gesture of saying, “I’m going to leave the Ovaries because the Ovaries are going to stop me from going into Menopause. So, take everything out but leave the Ovaries.”
Jeff: It doesn’t work like that, does it?
Matt: In reality, yeah, the Ovaries just shrivel up and do nothing anyway. So, the main thing is it’s inevitable that the Ovaries are going to stop making Hormones, so it’s very, very important to maintain your Adrenal status and the ability for your Adrenal Gland to continually make Hormones going into Menopause.
The amount of Hormones are not as important as the actual ratios between the Hormone, so it’s also very important to look at those and understand that a lot of the Menopausal symptoms that women get, and we’re just talking women for now, the Menopausal symptoms for women, it’s actually their body getting used to a lower level of Hormone. So, just jacking that Hormone up to keep them back to the same level of Hormones they had when they were getting a Menstrual Cycle is not necessarily the long term plan. You more want to get the body more sensitive to the lower level of Hormones and start regulating the balance.
So, typically, Progesterone drops off first and Estrogen stays high, and we can do things to enhance Progesterone activity or offset some of the Estrogen actions by changing from the 16 Alpha really toxic Estrogen to the weaker Anti-Estrogen that will protect the body. So, the strategies that you take are to actually maintain the ratios between Estrogens and Androgens, because the Androgens, which are DHEA, Progesterone and Testosterone they’re the ones that are going to maintain, in the women coming into Menopause, Libido, Motivation, Drive, and they do a lot to prevent against dryness. They also do a lot preventing hot flushing and all that sort of stuff.
Jeff: Not to mention Muscle tissue and body fat percentage?
Matt: Oh yeah, Osteoporosis and that. Because these Hormones are declining pretty much, you’ve got this opportunity to build really good quality Muscle and Bone up until the mid-thirties and then it typically declines. I mean we’re breaking those rules because we’re cheating.
Jeff: I was going to say, Matt, I refuse to accept that.
Matt: Yeah, don’t accept it because that’s statistical stuff. So, statistically speaking most people just about everyday life will peak their Muscle and Bone in their mid-thirties and that’s as much as they’ve got and then it’s going to decline from there. So, maintaining good Muscle and Bone up until that age period is the best way to prevent Osteoporosis.
Jeff: Yeah, and it’s funny, we talk about refusing to accept it. I was talking to Toni about this the other day about someone who was just turning 60, and I said, “When you look at these people,” and I’m talking about people who, particularly, don’t look after themselves, who aren’t eating well, who aren’t training, and you’re saying, “Well, that person’s probably considered to be old, or at least they look old,” but realistically, as far as I understand science, Matt, cell death occurs at 120 years of age; we can live to 120 and potentially beyond, but at the moment it’s 120 years until they find a way to circumvent cell death occurring at 120. A friend’s grandmother lived until she was 110, full faculties. Fred Snout, remember the World War 1 digger? He was the last World War 1 digger alive in Australia. He was still doing alright at 110, still going.
And, this is the thing, people don’t look after themselves, they accept, “Oh well, whatever is going to happen is going to happen.” So, how do we slow down the clock? How do we anti-age so that we’re still fit and healthy and strong into our 60s and 70s and beyond?
Matt: Well, there’s a lot of factors with that, of course, as you can imagine. But, that’s what you’re talking about, quality of life not extension of life?
Jeff: Yeah, well that’s right, you don’t want to live to 100 and start being sick at 40.
Matt: Yeah, exactly. You could have 80 years of misery if you live to 120.
Matt: But, the big point is, most aspects of aging are Inflammatory, and most Hormones are Anti-inflammatory.
Jeff: Yeah, that’s cool.
Matt: So, if you simply look at the fact that Hormones decline, with the same old Inflammation you’ve put up with your whole life, if you haven’t actually gone out of your way to correct the cause of that Inflammation and your Hormones decline, all of a sudden this stuff is going to break you apart. So, if you’re listening to this podcast and you’re in your 20s or 30s and you are managing Gut Inflammation, like not if you’re going out and treating the cause and trying to fix the bloody thing, but if you are just managing to control the symptoms only and you’ve got this rampant Inflammation running through your body, then when you get to those mid-thirties and heading towards Menopause and you don’t have the Hormones to control this Immune System and this Inflammation it’s going to start causing Cardiovascular Disease, it’s going to start contributing to Cancers, it’s going to start causing damage to the oily structures in your body and your Brain and your Arteries and all that sort of stuff.
Jeff: And, that can lead to other things like Alzheimer’s and Parkinson’s, that sort of thing?
Matt: Yeah, exactly. And, that’s what causes the lack of quality of life. So, you become Catabolic, you start breaking down Muscle Tissue, start breaking down Bone, then you get into this vicious cycle of Injuries and then resting, losing more Muscle Mass, which makes you get more Injuries, which makes you rest more, and you’re in a vicious cycle, the whole Move it or Lose it. And, that’s why Osteoporosis kills people, I mean crumbling bones is not killing them it’s the fact that people with Osteoporosis will get a fracture and then what happens is, they’re bedridden and then they die because they get stuck into this routine of having to rest and then they lose Muscle and then their Bone gets weaker, it’s crazy.
So, Anti-aging is about keeping our quality of life, keeping your Brain working, keeping your Arteries well, making sure that your Energy Production Pathways and your Cells and that sort of stuff are firing efficiently, and that way you get a good quality of life until you die.
Jeff: So, that’s mainly women with Menopause, but what about men, Matt, with Andropause?
Matt: Yeah. So, with Andropause men typically, we’re a bit luckier in the sense that we don’t have the issues with the bleeding, with no one there saying we need Hysterectomies, and I mean we do have to pop in and get a finger up the date and check out that.
Jeff: Well, you do.
Matt: I made my choice.
Jeff: Well, I’ve had to go in for the snip, and I mean that was terrible. I said to Toni, “You should have a Hysterectomy, I’m not going in there and have someone snip something.”
Matt: Yeah, well this is the discussion I’m having with my wife, she’s saying I should have a snip, but there’s evidence that the snip does have effects on male Hormone production going forward, where the Hysterectomy doesn’t for the women.
Jeff: And, major surgery with Toni, with Factor V Leiden, which is rare blood disease which causes clotting versus a 30-minute operation with a snip for me; I’ll take my point for the team.
Matt: My wife pointed out a similar thing with the surgical requirements and even the emergency room requirements for stabbing, because she will cut me.
Jeff: Yeah, I believe that.
Matt: Yeah, you’ve met her. She’ll cut me, she’ll cut you.
Jeff: Yeah, well she’s already threatened to.
Matt: I don’t doubt that, actually. I don’t doubt that at all. So, what were we talking about? Andropause. So, with men, typically from the ages of mid 30s onwards their Hormones gradually decline in a nice steady way. So, typically what happens there is we get a lot of imbalances with Testosterone as it’s declining. What happens is, the Dihydrotestosterone is so much more active than Testosterone so…
Jeff: So, the one that makes you bald, the pot belly?
Matt: Exactly. So, your body’s sitting there thinking, “Oh, the Androgen effects are declining, the Estrogen effects are staying high,” because we’ve had all this exposure to things that make more Estrogen. So, in men what happens is, Estrogen stays normal or even creeps up higher and the Testosterone effect drops off. The body, in its wisdom, says, “Well, I can amplify the effects out of this small amount of Testosterone I’ve got by converting it to Dihydrotestosterone.
Jeff: What are the benefits of Dihydrotestosterone?
Matt: Oh, really good for Muscle Mass. The guys on the gear for the DHT stuff it gets that real dry hardness. It turns you into a mongrel too, it gives you that real fire. But, it depends, people can choose their attitude, if you’ve got that ability.
Jeff: A friend of mine, when I used to say, “If guys getting onto the gear, it will turn you into an arsehole,” and he says, “No, not really.”
Matt: It will amplify the arsehole-ness.
Jeff: Yeah, exactly.
Matt: If you’re an arsehole you’re an arsehole, and if you’re a grub you’re a grub.
Jeff: It just takes you to that position of becoming and arsehole a bit faster, that’s all.
Matt: Yeah, but it’s still up to you to choose your attitude. So, DHD makes you Angry…
Jeff: Doesn’t that also help with Erections?
Matt: Oh yeah, it does Erections. Well, it does all the Androgen effects, it just amplifies it, but that causes problems with the Prostate, that causes Acne, that causes Baldness, it causes a lot of problems with Visceral Fat as well, a lot of fat in around internal organs which contributes to heart disease. So, it’s not a good one. Controlling the Conversion of Testosterone to Dihydrotestosterone can often preserve or slow down a lot of the side effects, or the symptoms that men have of Andropause, which is typically, becoming more Emotional, struggling to get the Recovery, the Regeneration and Repair, they have a lot more Aches and Pains and Joint Pain. You know, you do a hard day’s work, which normally you could back up with another one, and all of a sudden you’re just waking up feeling as though you’ve run a marathon.
Jeff: Right. It’s funny, actually, I heard a few women say as their husbands have got older that they’ve become cuddlier.
Jeff: And, I was reading somewhere that Testosterone destroys the cuddly Hormone or whatever that is.
Matt: Well, they’re getting too much Estrogen, in relation to.
Matt: So, ratios of these Hormones. So, as their Testosterone is declining because their nuts aren’t making it and the Adrenal Gland may be struggling because it’s been making Cortisol for so long just to deal with Work and Stress and all that sort of stuff. So, the Adrenal Gland can struggle to compensate and make enough Testosterone, so what happens is, the body then converts the Testosterone it’s got to Dihydro- and there’s always that Estrogen conversion which is more of an environment issue and as we get to 30 and 40 years of age we’ve had a lot more exposure to Plastics, Pesticides, Fertilisers, Xenoestrogens, and that sort of stuff, and maybe acquired some more fat.
Jeff: So, before we get into athletes and talking about Testosterone and Sex Binding Hormone, Globulin and Free Testosterone, what should pre-Menopausal and Menopausal women take away from this, and what can they do? And also, Andropause men, as well.
Matt: Well, it’s a tricky one because we’re talking mainly about Testosterone and Androgens around Menopause, because the Hormonal Profile varies from individual to individual. But, a typical thing that would happen, if a woman coming into Menopause doesn’t have enough Androgens the symptoms that she will see, specifically, are Depression, Fatigue, Lack of Motivation and Drive, Low Libido, Vaginal Dryness, and a lot of Aches and Pains, and the inability to control the body shape where they will hold a lot more Subcutaneous Fat on the hips and thighs. So, that’s the sort of change you would see with someone Androgen deficient coming into Menopause.
In that situation you want to support the Adrenal Gland to make good Testosterone production. The best herb for that is the Tongkat Ali. That ALPHA VENUS product that we make specifically helps to reduce the amount of Cortisol produced by the Adrenals and puts those resources over to DHEA and other Androgen producing pathways. So, it makes you more Anabolic, less Catabolic, that sort of stuff. So, that’s what women will see coming into Menopause if they don’t have enough Androgens.
Men, typically, will see the same sort of things, they get a lot more Subcutaneous Fat, but they get a lot weepier, Sadder, a lot more Emotional. In the clinic it happens all the time, you’re talking to the guys and then all of a sudden they listen to music and actually start—don’t watch Beaches and that sort of stuff.
Jeff: Like Huggies Ads and breaking into tears over babies and puppies.
Matt: Yeah. And, the guys they’ll be watching shows in TV and they’ll be crying with the cooks on MasterChef and all that sort of stuff.
Jeff: Oh dear.
Matt: But, typically, Testosterone also means they’re not Regenerating and Repairing, so a lot more Arthritis, a lot more Aches and Pains, a lot more Fatigue, Lack of Motivation and Drive; they just kind of lose their fire, their Libido drops, and of course Sexual Dysfunction and that sort of stuff will be a part of that, Impotence and lack of Desire and that sort of thing.
For men, in that sort of situation, what we’d want to do is use the ALPHA MARS, and that’s going to increase Testosterone production significantly.
Back to the women, because we get a lot of questions about women with ALPHA MARS.
Jeff: Yeah, thanks for reminding me.
Matt: And, it is a little bit confusing, but we have to understand herbs are that way, we’ve got to understand the nature of the beast and the way they work, and understand what these tools are good for. So, with ALPHA MARS the times that a woman would use ALPHA MARS is totally different to when a man would use it. You touched on it before when you mentioned Luteinising Hormone.
So, with Follicle Stimulating Hormone, in women, it makes Estrogen. Okay?
Matt: Now, ALPHA MARS increases Follicle Stimulating Hormone, which will induce and mature a Follicle in the women, it may induce a Menstrual Cycle to start again. So, if a woman’s Estrogen levels have dropped because of losing body fat, coming into comp, Stress, or coming into Menopause, or they were put on the pill too early and it’s just shut them down, then you can use ALPHA MARS to increase Estrogen as well as Testosterone, Progesterone and everything. So, it will increase your total Hormonal Load and your total Hormonal Production across the board. So you’ll get Estrogen, you’ll get Testosterone, Progesterone, you get everything out of ALPHA MARS for a woman.
Now, if you don’t want Estrogen don’t use that. But, if you’ve come out of competition and your periods have stopped most people would just use one bottle, and it will get their Menstrual Cycle started again. With that, comes a lot of Motivation, a lot of Drive, a lot of Energy—ALPHA MARS is brilliant for Energy. So, it’s very, very good for a woman to use that to trigger her Menstrual Cycle to start again after extreme Fat Loss or after extreme Trauma or after extreme Stress. But, you don’t need it forever, you just use it to kick the thing in.
Any other situations of low Estrogen, which might be confirmed on blood tests, for various reasons, and they’re usually just called Menopause, they just either say normal time or early. So, any form of Menopause the ALPHA MARS will stimulate Follicle Stimulating Hormone to tell the body to make a bit more Estrogen. It will also do Luteinising Hormone to tell the body to make the Androgen. So, that’s the only real time that women—like, I’ve got my mum on ALPHA MARS and ALPHA VENUS because she’s got a history of Estrogen Dominance, but she’s coming into Menopause. So, Mum’s got a history of the Breast Cancers and Abnormal Cells and that sort of stuff, because we’ve got that MTHFR Gene polymorphism in the family.
Jeff: Great, lucky you.
Matt: So, with Mum we give her the ALPHA MARS to get rid of all of her symptoms, and I’m positive it has no effect on her Libido, that’s just normal now. I don’t want to talk about that. Oh!
Jeff: I heard your mum is a Tyrannosaurus Rex.
Matt: Yeah, well stop texting her.
Jeff: Once she sees me who can blame her?
Matt: Oh! I don’t know how we got there. But anyway, ALPHA MARS can be used to fix Menopausal symptoms, it smashes Hot Flushes, Night Sweats, which are signs of low Estrogen, so Hot Flushes, Night Sweats, Dry Skin, Dry Hair, again, Vaginal Dryness, it fixes all that sort of stuff. But, if you are young and you have ample Estrogen and you have Estrogen Dominant Fat Tissue like bum and thighs and around the Glutes and the Hammies, the backs of the arms, love handles and that sort of stuff, using ALPHA MARS as part of your comp prep is not going to help you get rid of that Estrogen Fat. It will give you plenty of Energy, it will help your Recovery, it will help you build Muscle to a certain degree, but understand that ALPHA MARS in young women is going to make Estrogen, which is great, it’s healthy and all those sort of things, but it’s not going to help you with your comp prep.
Jeff: No, because it’s more inclined to make you softer.
Matt: Because, its making Estrogen in your blood. I’m going to tell you some crazy stuff a little bit later about how to use Estrogen to build Muscle, I’ll show you how to…
Jeff: Estrogen to build Muscle?
Matt: Estrogen to build Muscle. I’ll show you how to do it, and you’ve got to keep listening, I tell you. How Estrogen is more Anabolic than anything, it is the most Potent Hormone for Muscle Building. You don’t believe me?
Matt: That’s alright, I’ll show you references.
Jeff: Actually, I kind of do, but I’m intrigued.
Matt: I’ve forgotten what I’m talking about now.
Jeff: We were talking about ALPHA MARS for normal women.
Matt: Yeah, that’s right. So, ALPHA MARS can be used for women who want more Estrogen, and if you don’t want more Estrogen…
Jeff: Don’t use it?
Matt: Don’t use it.
Jeff: If you’re normal, right?
Matt: If you’re normal.
Jeff: Because, I did have somebody call me through the week, concerned, saying that there are some trainers that are out there absolutely loving our products, which is great, but they’re recommending to all the women coming up to a Comp, and maybe they misheard, maybe they’ve got some research that they’ve found, Matt…
Matt: Yeah, and that’s the other thing too.
Jeff: And, that’s fine, but from our advice always work with your healthcare practitioner, but our advice, Matt, is…
Matt: See, they might be thinking the same thing I’m thinking, where Estrogen is Anabolic.
Matt: Let me explain, let me simply explain.
Jeff: Do you want to jump into this now?
Matt: Yeah, why not. It’s exciting.
Jeff: So, let’s talk about SARMS and Estrogen and SERMS and everything like that.
Matt: Alright, that’s easy, man.
The fun thing is, Estrogen Receptors in Muscle—now, this is where I’ve got to explain it, you’ve got to put in perspective. Because, when Estrogen is in your blood it binds to Estrogen Receptors, but it’s just like throwing Estrogen all over the place and whichever Receptors pick up on it they’re going to Estrogen type things with it. So, specific Receptors do specific things, but they’ll just pick up on Estrogen, so ratios between which Receptors are fast, which Receptors are slow will determine if that Hormone is Anabolic and builds Muscle, or if it contributes to building fat depending on where you’ve got the most amount of Receptors, or which Receptor this Estrogen is actually hitting.
So, using something to increase Estrogen in your bloodstream does not necessarily mean you’re going to build all this Muscle. It more likely means you’re going to get fat.
Jeff: Well, I understand that, it makes sense so far.
Matt: Because, we know elevated Estrogen in the bloodstream can contribute to excessive fat and make it harder to burn fat, alright? But, they’ve discovered some Estrogen Receptors on Muscle Cells that stimulate Muscle Hypertrophy, increase the number of Muscle Cells and increase diameter of Muscle Fibres greater than Testosterone, Dianabol, Tren, SARMS, DHT, IGF1.
Jeff: Is this a relatively recent study, Matt?
Matt: We’ve know about it for a while because we’ve always known Estrogen builds bone and that sort of stuff, but everyone keeps looking at blood levels of Hormones and saying, “High Estrogen doesn’t build Muscle, it makes people fat.” But, now they’re starting to realise that different people, like for example, certain people who can have a nice muscular booty, and then other people who can have no booty, or a fat booty, will have differences in, not necessarily Estrogen levels in the bloodstream but Estrogen Receptor ratios on the cells.
Jeff: So, the question, therefore, “How do we either change or activate or…
Matt: Screw around with the Receptors.
Matt: Yeah, that’s the exciting bit. The funny thing is, where this research came from was, when they were trying to work out how Phytoecty Sterones, which we put in our PROTOTYPE 8, how they are as Anabolic as they are, because they’ve always known that they’re more Anabolic than Dianabol, but they’ve always said that they don’t actually work on the same Receptor, so they were trying to compare—they said, “Yeah, the end result is, yeah, substantially better, and doesn’t have any of the side effects, but how the hell does it do it?”
Jeff: Yeah, I remember.
Matt: And, the recent research was sitting there showing that it does it by binding into these particular Estrogen Receptors.
Jeff: That’s cool
Matt: Now, think about the booty.
Jeff: Oh, always!
Matt: Okay, now let’s get back to what we were talking about. So, if you think about it, there’s genetically and ethnic different variations and where people are from.
Jeff: Yeah, I mean they talk about the Asian butt.
Jeff: And, then you’ve got heart shaped bums, and you’ve got all sorts of different—Matt’s hairy butt.
Matt: Yeah, all those sort of things. So, the ability to modify Estrogen Receptors in Muscle Tissue is your ability to build specific types of Muscle in specific types of locations. So, we can go through and screw—now, you know, is it a coincidence…
Jeff: A Brazilian booty?
Matt: Exactly. Is it a coincidence that the older body builders struggle with Quads, that’s their weakness?
Matt: They’ve got to build as much Quads as they possibly can when they’re younger because it’s going to start to decline as they age.
Jeff: Well, they say over 40; Mick Galle was saying that.
Matt: And, it’s all these Hormones are all dropping off, and then, what do they supplement with? Just the Androgens.
Jeff: Yeah, I was going to say, Testosterone, typically.
Matt: Can you imagine if we started to use Estrogen Receptor Modifiers in aging athletes to be able to continually build good Quads, Glutes and Hammies. Can you imagine being able to create a protocol where we can specifically manipulate with Estrogen Receptors to target a booty building campaign?
Jeff: Well, what impact, then would something like PROTOTYPE 8 have on your bum, not just talking about women but guys too, I guess? If your theory is correct, or the research is correct, which I’m not going to doubt, what impact will it have on fat on the bum, then?
Matt: Well, this is the wild thing; some Estrogen Receptors cause Insulin Resistance and hold fat and hold fluid. Other Insulin Receptors, like Insulin Receptor Beta, that one there will directly have a positive effect on Insulin Sensitivity and start dragging the carbs through to Regenerate Muscle Glycogen instead of converting it to fat and storing it in the local tissue. So, you can imagine, in the booty—not in the booty, but the cheeks of the booty, the Glutes and the Hammies and that sort of stuff?
Matt: We will have Fatty Tissue, Muscle Tissue, you’re going to have Estrogen delivered by the bloodstream to that area, you’re going to have Muscle and Fat in that area and Bone and Arteries, and they’ve all got Receptors for these Hormones and they’re going to pick up on these Hormones. So, rather than throwing extra Estrogen into the bloodstream, if someone’s predisposed to holding fat on their booty…
Jeff: Yeah, a lot of girls are, and some guys are.
Matt: …and, you put extra Estrogen in there—yeah, but some girls aren’t, that’s what I’m saying. So, some people can have the same level of Estrogen as someone with a big fat bum, but they will get a hard booty, and others with the same amount of Estrogen will get Cellulite.
Jeff: And, be lean everywhere else?
Matt: Yeah. So, this is what I’m saying, it’s Receptors and the number of Receptors and the sensitivity. So, the males have been using SAMES for years, which are Selective Androgen Receptor Modifiers.
Jeff: Yeah, I’ve heard a lot of SAMES.
Matt: So, I’m talking about SERMS.
Jeff: Yeah, I’ve heard a little bit about SERMS.
Matt: So, I’m talking about Selective Estrogen Receptor Modifiers, except, they’ve always done the research on SERMS for things like Breast Cancer, Hot Flushing, boring stuff—I mean, not boring, like important stuff that keeps alive. But, the research is now starting to go onto these SERMS and how they can fix Osteoporosis, and on the back of that research they’re starting to find all these effects on Muscle Mass. Because, your Fracture Risk and your Osteoporosis Risk is proportional to your Muscle Mass. So, they’re starting to find if we can maintain big Muscle Mass—and, they’re finding, guess what? It’s the same Receptors.
Jeff: Yeah, it’s wild.
Matt: And, it’s wild because all the early research on Phytoecty Sterones was showing a massive ability to Regenerate Bone, so it’s starting to link in with this particular SERM effect from the Phytoecty Sterones. Now, what’s interesting about it is, a lot of people out there will use Anti-Estrogens because, like we were saying before, Estrogen holds Fat and Fluid in certain areas. But, when these people use Anti-Estrogens like Arimidex, Tamoxol, pharmaceutical Anti-Estrogens, they lose massive amounts of Muscle.
Jeff: Yeah. I’m not going to mention who, but when I was a lot younger and I was using some gear they were always saying, “Never use your Tamoxifen or your Nolvadex or anything like that with your gear unless you absolutely have to, you get puffy nipples, because you will reduce your gains.
Matt: Yeah. Yeah. And, it’s because it’s been known forever that you need Estrogen to build Muscle. Now, what I’m saying is, we can use things like ALPHA VENUS to regulate the type of Estrogen that’s in your bloodstream.
Matt: So, with ALPHA VENUS it won’t screw around with how much Estrogen your body makes, because what happens is, your body makes the right amount, it does what it’s supposed to do, the ALPHA VENUS then strips it out, changes it to a form that won’t hold Fat and Fluid. So, we can use the ALPHA VENUS to control their Hormonal Profile in the bloodstream.
Jeff: So, you’re not getting too much of the bad Estrogen?
Matt: Exactly, that will cause Fat and Fluid on the bum. And, at the same time we use the PROTOTYPE 8 that’s got the Phytoecty Sterones to go in and have an Estrogen Receptor modifying effect by stimulating the Estrogen Receptor Beta on the Glutes and the Hammies. So, that combination you can actually reduce the amount of Cellulite Inflammation, Fat and Fluid held in the Fat Cells on the Glutes on the Hammies at the same time as directly stimulating the Estrogen Receptor Beta that will fix up the Insulin Resistance in the local area, it will encourage all of those Nutrient Deliveries into those cells. It’s a very powerful Anabolic, so you can create Estrogen-type Muscle and get rid of Estrogen Dominant Fat in the same location with the right pushing and pulling.
Jeff: It sounds too good to be true, Matt. People are going to get pretty excited when they work this out.
Matt: Yeah. Well, people are seeing the results, it’s just…
Jeff: They didn’t know why?
Matt: Yeah, and the feedback is coming back that they’ve never seen anything like it, it’s witchcraft and all that sort of stuff. But, you know, this is thing…
Jeff: “What kind of sorcery is this?”
Matt: Yeah, I know.
Jeff: “It’s science.”
Matt: Yeah, it’s wild to think that we can have that ability, and it’s freaky because—okay, just that simple concept that Estrogen Receptors can control Insulin Sensitivity in Muscle where we know—how many times a day do we get asked about Polycystic Ovaries where these people are getting too much Testosterone and they’re having problems with Insulin, they’re holding Fat, they’re breaking down Muscle, and their problem is, they’ve got too much Testosterone.
Matt: So, this is what I’m saying, Receptors and all that sort of stuff is so important. So, it’s wild.
Jeff: PROTOTYPE 8, I can see that’s going surge with women, now, big time.
Matt: Yeah, but what I’m hoping is, the men understand the importance of Estrogen for building Muscle. Holy hell, did you ever think you’d ever hear me saying that?
Matt: It’s so important for men, especially men that want to maintain good Quads and Hammies and everything, how important it is for them. Now, I had a good chat with Dave Palumbo, while we were in America, and he made some really valid points, by saying, “But, at the end of the day, you can’t build the wheels if you can’t squat the weight.” So, it’s one thing to say, “Yeah, we can screw around with Hormones and that sort of stuff to increase your potential for building Muscle and burning Fat, but if you don’t have the physical capacity to carry that load then you’re not going to get the gains.” So, that is again, why it’s so important to get the gains while you can.
Jeff: While you’re young, yeah, or if you’re a bit older.
Matt: But, when we questioned, “Why can’t we lift the weights?” then we’re talking about Injuries, we’re talking about Inflammation, we’re talking about wear and tear, and that’s when we’re also talking about maintaining good blood levels of Hormones, maintaining Receptor Sensitivity will control Inflammation, controls Regeneration and Repair and may prevent the Injuries that are occurring as your Hormones drop.
Jeff: It ties in nicely, Matt.
Matt: Yeah. And, that’s why back at the start we were saying all aspects of aging are Inflammatory. We take the Inflammation out then you keep that quality of life, you keep that ability to keep lifting and keep that strength and prevent the Injuries and you’ll keep going, especially if we’re keeping the Hormones and that sort of stuff working well. It’s an interesting concept, and that’s why we’re saying, “Forget what we thought we knew because things…
Jeff: It’s paradoxical, almost, to what we used to think.
Matt: I know. And, there was that whole phase of Anti-Estrogen, Anti-Estrogen, and that’s why I don’t like people talking about ALPHA VENUS as an Anti-Estrogen product. It’s a specific product that allows Estrogen to do it’s good things, but then strips it away so it’s not stored as fat.
Jeff: And, that’s the problem, I think, Matt, with DIM too. Because, it’s just one active component in isolation as opposed to—yeah.
Matt: Yeah. And, the big problem with DIM, because you’re using one active ingredient in a larger dose, and it’s not just one because it converts through to so many other things, but DIM has research on how it blocks Androgen Receptors more powerfully than it detoxifies Estrogen. So, that’s why ALPHA VENUS works better than DIM anyway. Plus, with ALPHA VENUS the other thing that we always get asked is, why didn’t we put Calcium-D-Glucarate in it. But, the reason why we didn’t put—well, a couple of reasons, one is because we’re in Australia, and Calcium-D-Glucarate is easy to put in, but all it does is it keeps the Estrogen that’s already bound, it keeps it bound.
Matt: But, what we’ve got in our product is Kelp and Rosemary, they both do exactly the same thing as Calcium-D-Glucarate, so it’s a neat little system.
Matt: The other thing that I wanted to mention to is, we’ve got another version of ALPHA VENUS coming out.
Jeff: Yeah, look Matt, that’s probably going to be a full on podcast just on what we’re doing with the ALPHA VENUS. We can mention it quickly now, if you like.
Matt: No, I don’t want to now. If anyone’s interested in a little bit of something, I almost said, you have to listen to the next podcast.
Jeff: No, come on you big baby, say it then.
Matt: No, I’ve spat the dummy. I was going to say something—no, I can’t remember which one is which.
Jeff: Let me start talking and you’ll remember, that’s what normally happens. Well, don’t you have to twiddle your hand off to the right and that activates the part of the brain that gets short term memory firing again?
Matt: Look up to the left.
Jeff: I don’t know. But, anyway, we’ll be putting Vitex into the ALPHA VENUS and we’re stripping out the Tongkat Ali, and this is in the ALPHA VENUS pink, simply because we’re having so many people, now, that are coming to us with Polycystic Ovary Syndrome, PCOS. And, Matt, you might have known, but for me I am absolutely blown away by how many people have got issues with regards to Polycystic Ovarian Syndrome.
Matt: And, it’s not just Polycystic—the Insulin Resistant Syndrome is the reason why we’re done it. Because, the Insulin Resistant Syndrome they now believe is affecting one in four people.
Jeff: That’s crazy.
Matt: The Insulin Resistant Syndrome includes Polycystic Ovarian Syndrome, it includes Type 2 Diabetes, people with High Cholesterol, but also Acne, Hirsutism, you know, the bearded ladies?
Matt: So, all that sort of stuff there, that is associated with the Insulin Resistance Syndrome, and that is one if four people. So, what we’ve done is, we’ve taken out the Tongkat Ali because…
Jeff: That won’t be available until probably early next year, so 2016.
Matt: Yeah. So, basically we’re going to have ALPHA PRIME which is the ALPHA VENUS as it is now, is that right?
Jeff: Okay, ALPHA VENUS is so popular and the pink label has become iconic and women look for that, they recommend it, “Go get the one with the pink label.” The new ALPHA VENUS will be suitable for any women, and women only. It also contains Vitex, and Matt you might want to talk about that in a minute. The ALPHA PRIME is the ALPHA VENUS grey.
Matt: The original.
Jeff: Which is exactly the same as the pink but it is designed to use for males, because most males, unless Jimmy, won’t use something with a pink label.
Matt: And, the other thing is, the ALPHA PRIME…
Jeff: Yeah, which is the ALPHA VENUS grey, which has got the Tangkat Ali.
Matt: That is suitable for women that want to get a little bit more Androgen activity so they can build extra Muscle and strip out extra Fat, which is a smaller percentage of the women, who are more concerned with stripping out the Estrogen to get rid of the Fat and having a healthy Menstrual Cycle and that sort of stuff.
Jeff: That’s exactly right.
Matt: Vitex Agnus-Castus is one of my favourite herbs.
Matt: It increases Progesterone production, so it improves the quality of Ovulation and enhances the production of Progesterone. And, Progesterone has a very positive effect for Polycystic Ovarian Syndrome, it’s brilliant to help treat that, but it also means that if the body does need extra Testosterone it can make it. So, Progesterone is an Androgen and it can use that as a pre cursor for Testosterone production if it wants to.
Jeff: So, the ALPHA VENUS, the new one, the pink—and, by the way, we’ve got a complete label change coming early next year.
Matt: Yeah, so it won’t be confusing.
Jeff: Yeah, it won’t be confusing, even though we’re confused ourselves. Is it still suitable, and will it be suitable for women who are Premenopausal and Menopausal too, Matt?
Matt: Yeah. Yeah, brilliant.
Matt: And, it makes you feel awesome because, Vitex increases Dopamine in your brain and that does Self-esteem, Pride, Reward, and all that sort of stuff.
Jeff: For women, right?
Jeff: It’s not so good for guys?
Matt: No, blokes don’t usually use Vitex.
Jeff: Why is that, Matt?
Matt: Well I don’t know. There’s Vitex I’m seeing popping up in test boosters and that, for men, now.
Jeff: Why are you smirking?
Matt: Well, one of its common names is Monk Berry, and the reason why I researched that, and wondered why they called it Monk Berry is because the Monks used to eat it to suppress their Libido.
Jeff: Oh. That’s not something I want.
Matt: No. No, but it doesn’t have that effect on women, apparently it has the opposite effect.
Jeff: So, we’ve covered off on Andropause and Menopause.
Jeff: And, Matt, do we want to talk about, and we have in the previous episode about Testosterone, we’ve talked about Zinc, we’ve talked about Magnesium, we’ve talked about the other substrates that your body needs to produce Testosterone. Is there anything else that you want to cover off on those base things that we need? Zinc, Magnesium, Boron, anything positive that you can take? I think we’ve covered off on a lot of it previously.
Matt: Zinc is so damn important. I find myself, almost every day, telling people to supplement with extra Zinc. It’s one of those things that if your body needs it, it will absorb it more readily, and as your levels top up you don’t absorb as much, so it’s hard to really take too much.
Jeff: Why is Zinc so important? I mean, a lot of people are taking Zinc and Magnesium, Vitamin B6, which we know as three quarters of what they need to be taking, we’ve got a new product coming out.
Matt: For that particular Enzyme.
Jeff: Yeah. But Zinc, Matt?
Matt: There’s over 500 different Enzyme systems that Zinc’s involved in. So, to simplify why we need Zinc, is anytime you’re building stuff, or anytime you’re breaking stuff apart, it involved the Enzymes that utilise Zinc.
Jeff: So, the Endocrine System runs on Zinc?
Matt: Everything, yeah. Everything; it’s your Digestive System, your Immune System, your Regeneration and Repair, everything. We don’t hold much Zinc in our body and we’ve actually got to replenish it readily because we lose so much.
Jeff: Is it true, Matt, or is this an old wives’ tale, look at your fingernails and if you see any white specks that may be a Deficiency in Zinc?
Matt: Yeah, it may be a Deficiency in Zinc, and the other things that can cause…
Jeff: How many people are right now looking at their fingernails seeing if they’ve got…
Matt: We’ve got two in this room.
Jeff: Yeah, me too.
Matt: The thing is, with the white spots you can also get white spots if you bash your finger, so from Trauma, you can also get a weird type of white spot which is too much Calcium. Otherwise Zinc Deficiency, and you can tell because it’s kind of a weird one that appears from under throughout the nail and then as you top up Zinc it fixed up. Calcium and those Trauma ones you can tell; it looks like you’ve damaged the nail. So, that’s that.
Jeff: Magnesium as well too, Matt? I mean, typically, those things are normally taken—they work quite well together, don’t they?
Matt: Yeah, well Zinc, Magnesium, B6, and there are a few other co-factors, that are missing from that, to get your Enzymes to work.
Jeff: And, when you’re taking your Zinc you want to minimise the Calcium intake at the same time because they can…
Matt: So, this is the thing: Zinc binds to Calcium, Magnesium, Iron. So, when you use a cheaper form of Zinc, well not a cheaper form of Zinc, it’s got nothing to do with how much they cost, but when you use an Inorganic form of Zinc—it’s hard, some forms of Zinc that dissociate in the stomach the Zinc can be floating around at the same time as the Iron, Calcium, Magnesium and everything, so then they will bind together.
Jeff: And, then their absorption is reduced?
Matt: Yeah, because they’re stuck together and they pretty much go straight through. Zinc will also build to Phytates and Oxide.
Jeff: What’s a Phytate?
Matt: Phytates come in a lot of fruit and veggies and Oxalates that are found in cereals and grains.
Matt: But, if your body is Deficient it will rip the stuff through…
Jeff: It will suck it up.
Matt: …because it’s desperate for it. Zinc Gluconate is good, Zinc Citrate is good, Zinc Sulphate is not real flash. Chelated forms of Zinc are good; Chelated forms of Zinc, which is a Zinc Diglycinate, those things their absorption is a little bit better even if you have then around those other Iron Foods and everything. And, my favourite one is Picolinate, because the Pancreas actually makes it into Zinc Picolinate to help the absorption, so when you give another form of Zinc the Zinc floats around, the Pancreas uses Tryptophan, B6, Magnesium, Zinc and that sort of stuff to make a Picolinate form, and that will absorb it in the Picolinate form. So, you can go straight in with Zinc Picolinate and it tends to get absorbed, and you can force extra levels of Zinc in that will normally make you feel a bit queasy.
Jeff: Right. So, Zinc is very, very important.
Matt: Have you ever done a Zinc taste test?
Jeff: Yeah, I have, it makes me feel sick.
Matt: What that means is your Zinc level is probably okay. So, Zinc Sulphate they tip into your mouth and if you don’t absorb it, because you don’t need it, it stays on your tongue, and it’s a minerally, furry sort of thing like you just licked the carpet.
Jeff: It’s disgusting, yeah, I hate it.
Matt: Lick the carpet and then compare it.
Jeff: I have.
Matt: Or, munch boxers.
Jeff: Magnesium is important as well. What about Boron, Matt?
Matt: Boron is fine, but don’t buy Boron in Australia.
Matt: A few years ago there was all this research coming out that Boron is great for Osteoporosis and all that, but in the TGA in Australia they had—so, in Australia they’ve got a list of things that people have already added to this list and they’ve gone through the dramas to prove that they’re not killing you and all that sort of stuff, and then they’ve got everything else. So, for Boron, on that list, the only one they’ve got on the list is Borax, which is a cockroach poison, and for some reason that’s actually on the Therapeutic Goods List.
Jeff: Oh, so that’s good for you?
Matt: No. No, it’s a cockroach poison.
Jeff: Yeah, but the TGA says.
Matt: Yeah, yeah. So, someone’s paid TGA to get that on the list to show that it’s not poison, it’s therapeutic. But, all the research has been on other forms of Boron, not the Sodium Borate, I think it is, which is also known as Borax. So, in Australia they go through and load up—and, the doses of Boron in the studies that showed to be pretty good, we’re looking at a few 100 micrograms, not 1000 micrograms or milligrams.
Jeff: Really? I mean again, Matt, my research is not your research, my research is magazines and Google and other things like that, and you just rip it to bits. But yeah, I think there was one that was showing a few milligrams of Boron could help to free up Bound Testosterone.
Matt: While we’re in Australia and manufacturing products in Australia I haven’t done a whole heap of research on Boron recently, because we get plenty out of our foods, and if we’re eating the right ones then there’s no point getting it out of a supplement because it’s cockroach poison.
Jeff: Yeah, well in Australia that’s right.
Matt: So, you can get it from overseas.
Jeff: What foods, Matt? Do you know off the top of your head?
Matt: A lot of nuts and seeds and that sort of stuff, from memory.
Jeff: Okay. Alright.
Matt: You only need such small amounts, you know.
Jeff: So, that will do it. What about, Matt, the effect of Sex Hormone Binding Globulin and Free Testosterone for the athletes, as well too? This is something that I constantly used to get asked about, “How do you free up more Bound Testosterone?” and the role of the Sex Hormone Binding Globulin. And, we did cover this in the first episode, so again, we don’t need to spend a lot of time here. But, freeing up Bound Testosterone?
Matt: So yeah, Bound Testosterone doesn’t help you, it’s bound. We need the Testosterone to be free so it can work. So, basically, some people that have got low levels of Testosterone and the associated symptoms of that is because they’ve got too much Sex Hormone Binding Globulin. So, in that situation, what you want to be doing is dropping the Sex Hormone Binding Globulin and that will increase their Free Testosterone. So, the best is to lower Sex Hormone Binding Globulin, the most powerful one is Tangkat Ali, but a lot of the other herbs in that ALPHA MARS sort of product that frees it right up.
Then, there’s the other side of the story; you know when we were talking about the Insulin Resistance Syndromes and things like that, they’ve got too much Testosterone because they’ve got no Sex Hormone Binding Globulin activity, so all their Testosterone is free and running around doing weird stuff.
Jeff: You’d think they’d be like Brahman Bulls then, but that’s not the case.
Matt: No, it’s not the case because of Hormonal Ratios and that sort of stuff is so important. The weird things is, and I don’t understand fully why it’s happening, a lot of this research is sort of new, and I’ve got my theories, which I’ll probably push onto people anyway.
Jeff: Well, I’ll subscribe to your theory, Matt.
Matt: Because, basically, Hormones are Anti-Inflammatory, you know how I keep talking about that. So, one of the most powerful things to drop Sex Hormone Binding Globulin is Inflammation. So, excessive Inflammation—Cytokines, which are chemical messengers from the Immune Cells, Adipokines, which are chemical messengers from fat cells, they trigger the most Inflammatory messages through to the body and that lowers the Sex Hormone Binding Globulin and frees up the Testosterone. I don’t know if the body’s doing it to give more Testosterone to take control of the Inflammation, because it’s basically…
Jeff: Because, you said before that Testosterone is Anti-Inflammatory?
Matt: Yeah, and it helps Regeneration and Repair.
Jeff: So, it’s almost like a natural Immune Response?
Matt: Or, a Healing Mechanism. So, if your body’s had Injury, had Trauma, you’d normally get Inflammation and your body then would free up the Bound Testosterone so you can Regenerate and Repair faster. You know how we talk about training, it breaks you, and then it frees up your Testosterone to rebuild you faster.
Jeff: Yeah, right.
Matt: So, Inflammation frees up Testosterone. Now, so Fat makes Inflammation, Toxins make Inflammation, Insulin makes Inflammation, you know, there’s all of these sort of compounds. The Fatty Liver probably puts more Inflammatory mediators into your body than anything, which is why excessive Fat in the Liver is the major cause of low Sex Hormone Binding Globulin, high Testosterone, and may be the causative factor behind Polycystic Ovarian Syndrome, Acnes, Hirsutism, and all that.
Jeff: What would it do for guys, then?
Matt: What’s that?
Jeff: Well, that’s mainly for women with the Polycystic Ovarian—mainly women—well, for women. But, what does a Fatty Liver do for blokes then?
Matt: Well, it will lower the Sex Hormone Binding Globulin, it will increase Free Testosterone.
Matt: Yeah, wild huh?
Matt: Well, you’ve got to understand, you know how we talk about the Turtle Belly, that’s what we’re talking about, Fatty Liver.
Jeff: So, then the Free Testosterone, does that then create more DHT production?
Matt: Yeah, because the Testosterone is free and available to enter into the cells and convert it through to Dihydrotestosterone.
Jeff: And, I guess, if the body doesn’t have a huge use for that it forms…
Matt: And, it forms a vicious cycle because it makes heaps of Visceral Fat, makes a Fatty Liver which contributes more Inflammatory mediators, Adipokines into the bloodstream, which increases Testosterone, drops Sex Hormone Binding Globulin, makes you fatter in and around your internal organs.
Jeff: That’s interesting, isn’t it? Again, it comes down to balance and ratios.
Matt: Yeah, it’s ratios and balance and understanding that if the body is causing weird stuff to happen just research it and find out why and put in a strategy to prevent that.
Jeff: Alcohols, Drugs, and things like that, impact on Testosterone. Let’s talk about Alcohol, that’s a pretty easy one. I mean I know, from my understanding, it increases Estrogen and that can have a negative effect on Free Testosterone.
Matt: Well, certain Alcohols contain Phytoestrogens which are SERMS, Selective Estrogen Receptor Modifiers, but they have an exaggerated effect on holding Fat and Fluid. The other thing Alcohol does is it up regulates certain Cytochrome P450 Systems that strip the Testosterone out, so you have an Estrogen action at that the same time as you strip out the Testosterone, that causes an exaggerated Estrogen effect from the Alcohol.
Jeff: Yeah, that makes sense. Matt, anything else that you want to talk about in relation to Testosterone. We’ve covered a lot for Menopause, we’ve covered a lot for Andropause.
Matt: What were you asking me about Fibre?
Jeff: Fibre and its impact on Free Testosterone. There was some research that was suggesting that if you consume too much Fibre in your diet it can actually drop the amount of Free Testosterone in the body.
Matt: Yeah, right.
Jeff: What’s with that?
Matt: So, specifically Free Testosterone makes sense, because what I said before about the Inflammatory Cytokines, especially the ones from the Liver, they will drop Sex Hormone Binding Globulin and free up the Testosterone. What Fibre does, Fibre feeds the Bacteria in your Gut, converts it into Short Chain Fatty Acids, things like Butyrate, Propionic Acid, that sort of stuff, and they go straight into your Portal Vein to your Liver and have an Anti-Inflammatory effect on the Liver, increases Sex Hormone Binding Globulin and that will Bind up some of that Testosterone. It makes Fibre very important for the Polycystic Ovarian stuff, and the Insulin Resistance again.
Jeff: And, the Insulin production?
Jeff: And, I know that a lot of the top coaches, Chris Thomas, Fibre is very, very important to help to Bind Estrogen [0:58:03], but it can have an impact on Free Testosterone which is interesting as well. But, again, it’s that balance thing, isn’t it?
Jeff: I mean you don’t want to say Fibre is bad, I mean how many people are dying from dying from Bowel Cancer because they’re not getting enough.
Matt: Yeah, Chris Thomas is also using strategies with things like Berberine for the Polycystic Ovarian people. It’s a cool herb that we don’t use as much because it increases Sex Hormone Binding Globulin and lowers your Free Testosterone, so for most people it’s bad, but with Polycystic Ovarian Syndrome it works better than things like Metformin. It’s something very interesting I learnt from Chris on that, I think it’s excellent.
Jeff: Yeah, good work, Chris. Good stuff. Anything else, Matt, on Testosterone that we can talk about?
Matt: So much that we’ll probably keep talking about it every couple of podcasts.
Jeff: Well, Matt, that brings us to some FAQs.
Jeff: So, I’ve got a couple here from Beck; Beck’s being a little bit greedy, but here we go:
“Hi, I’ve just discovered your ‘padcast’ and love…
Matt: What did she discover?
Jeff: Our podcasts.
Matt: Our ‘padcast’?
Jeff: Shut your face. “I’m totally addicted and have been playing them whilst running, driving to work and whilst doing my housework. I have been competing in figure comps for a couple of years now but find it hard to get my legs looking as lean as my upper body. I’ve got as low as 11% body fat and my legs still aren’t showing a lot of definition even though I’m taking ALPHA VENUS for women, I’m half way through my second bottle. I’m a little bit worried about going lower than 11% and was wondering if one of your Transdermal Creams would be useful?
I also teach pole dance fitness classes and cannot use moisturiser on days that I have pole dance as it makes my skin too slippery.
Matt: Oh yeah, man.
Jeff: That makes sense. “Are any of the Transdermal Creams less oily than another, or I thought maybe to use the BLOCK E3 as a once a day application.
My final question: I went off my contraceptive pill onto a non-Hormonal copper intrauterine device and started the ALPHA VENUS to help detox the Estrogen from my body. But, since using the ALPHA VENUS I haven’t got my period. I have been around the same body fat for a Comp while still on the pill and still had normal periods, so I thought it must be my fat levels. Can ALPHA VENUS cause this or is it maybe just my body adjusting to being off the pill…Beck”
Matt: Okay. So, with the legs, when you’re looking at your body fat percentage being a certain amount, what we want to do is just specifically target that weakness and strip that fat off the legs for you. The way to do that, with ALPHA VENUS some people need, if you’re Deficient in Folic Acid and B12, it can’t work to it’s potential, so I suggest, for you, to add in an extra Folic Acid, about 1000 micrograms of Folic Acid.
Jeff: Once per day?
Matt: Yeah, once a day in the morning. It’s easier to find a good multivitamin that’s got these in them, as well as all the other B Vitamins, so you’re not taking just a couple of the B Vitamins out of ratios from the full B Complex. So, look for a good multivitamin that you can achieve 1000micrograms of Folate, and often they’re in 4 or 500micrograms, so you just take two. So, we want 1000micrograms of Folate, 1000micrograms of B12, we want about 30 to 50millegrams of B6, that will work with the ALPHA VENUS to make sure that the Estrogen is stripping away effectively.
The problem is, if you’ve had a stubborn area of Subcutaneous fat on the legs for a long period of time it becomes a weird little isolated…
Matt: Yeah, your body doesn’t even know it’s going on. So, the VENUS is controlling your ability for your Ovaries and your Pituitary Gland to regulate how much Estrogen is available for that, and the ALPHA VENUS is controlling the way your Liver and your Elimination Pathways strip that stuff out.
Jeff: So, that’s all the backlog problem, the upstream problem is fixed?
Matt: Yeah, but it may not, necessarily, be breaking the back on that local tissue, because it may not, necessarily, be getting to it effectively. Or, it may not be addressing the problem, which is the fat. What I mean by that is, that fat may have been made at some stage when your Hormones went out of whack or you just put on weight. That fat that’s on your legs–if you can just imagine the fat cells themselves are converting the Testosterone in your body to Estrogen in that fat cell on your hips.
Jeff: Mm, it’s got its own little ecosystem.
Matt: This isn’t talking about Ovaries, I’m not talking about Pituitary Gland, I’m not talking about anything. I’m talking about the fat cell less that 2mls under your skin that extends down towards the Muscle layer can be converting your Testosterone to Estrogen in that fat cell, and that Estrogen in that fat cell will make that fat cell fat, okay. And, it will use that Estrogen right there, not even send it back to the body, and what it will do there is make more fat cells, and guess what those new fat cells do? They make more Estrogen. So, you can have everything going right through the Pituitary Gland, the Ovaries and the bloodstream, but you can have this weird little Estrogen reservoir on your hips and thighs that is making the Estrogen that is making the fat this keeping your legs exactly the same regardless of what you do.
So, the key is to treat it locally, to target it with the Transdermals. So, your intuition is 100% correct.
Using a Transdermal product will have a different strategy and help to break the cycle. The one I would recommend would be the BLOCK E3, and the reason why is because it specifically targets the Estrogen issues that you’re talking about, but it’s non-greasy, and the best time to use it is not around training, it’s best after a shower twice a day. So, get out of the shower in the morning and night and butter up with the BLOCK E3 onto the thighs, Glutes, Hammies, lower back, especially, lower abdomen, and you’ll see major changes there, especially if you continue to use the VENUS and the Folates and everything. So, keep on the VENUS, add the Folate, the B12, the B6, throw in the BLOCK E3, and you should be able to break the cycle.
Jeff: Sounds like a plan. Alright, thanks Beck. Now, Beck has actually come back and written another email, and it’s a good one, so I think we might well use this as a bit of a case study to see if we can help her, Matt.
Jeff: So, as per any time when we’re giving advice please take this as information only and seek your healthcare practitioner’s advice. It’s difficult to know, we can’t see you, typically you need to talk to someone and really get into things, but this is a pretty in-depth…
Matt: We just give you some things to lead a discussion.
Jeff: To consider, yeah, and go from there. So, that being said, let me read the question:
Beck: “I’m waiting on some advice on what supplement to get my mum. She has raised seven kids, as a single parent—Wow, she needs a medal just for that—the youngest, of which, has Asperger’s Spectrum Disorder and is a very difficult and often angry teenager. My mum understandably is very stressed and takes the Antidepressant Pristiq. She also has Rheumatoid Arthritis as well as Dupuytren’s Disease—I hope I’ve pronounced the correctly, Dupuytren’s Disease—but refuses to take any prescription meds other than a few pain killers. The doctor tries to dose her up on these but she doesn’t like the drug’s affects so she doesn’t like taking them. She is Postmenopausal, although she doesn’t seem to get too many Menopausal symptoms. She also tends to carry weight around her midsection.
Blood tests confirm that she is Salt Deficient even though she uses enormous amounts of various rock salts on her food. I wanted to trial her on one of your supplements. On your podcast you mentioned ALPHA MARS and CORT RX are good Anti-Inflammatories. My mum wouldn’t be able to afford to take both so I wanted to know if the CORT RX by itself would be better to take on its own.
Also, would any of your products help my brother with ASD, which is the Asperger’s Spectrum Disorder?”
Thanks Beck for your question, that’s pretty full on. Matt?
Matt: Yeah, I agree she needs a trophy not a supplement. But, maybe a supplement as well.
There are a couple of weird little connections there, and of course, we can’t just—there is so much more…
Jeff: Diagnose or treat…
Matt: Oh yeah, that boring stuff. But, there is just so much more information we would require to try to work out which comes first. But, some of the interesting little links that I picked up from what you said there, that disorder…
Jeff: Dupuytren’s, yeah.
Matt: Has anyone ever had Plantar Fasciitis? You know, there’s Fascia on the soles of our feet and on the palms of our hands that control our ability for our toes and fingers to flex. Basically, with this disorder it Calcifies and you get big strips of hardened leather running through the palm of the hand that pull the fingers down, keeps them in a weird position. But, the funny thing is, that exact same symptoms can come from not enough Salt. It’s funny that she mentioned that the blood tests are always showing up Low Sodium because one of the classical features of Low Sodium is the Claws, people get Claw Hands, and it start with the little finger. It’s bizarre because the symptoms of Low Sodium are exactly the same as that disorder. It’s just that with that disorder the classical disorder is when they feel the Fascia in their hands it’s all calcified lumpy gristly stuff, but that happens when you start cramping anyway.
Matt: Anyway, I’m not saying you don’t have it when you’ve got it, I’m just saying if you fix up the Sodium thing it would be interesting to see what happens, it might displace some of the Calcium but also it stops the spasming and the cramping of the Muscle. Now, what’s interesting is, if you are eating Salt and you’re coming up Low Sodium then we need to start looking at why the hell your body’s not holding onto that Salt.
Jeff: The Sodium Pumps, Matt?
Matt: Yeah, possibly, or too much water. The most common cause of Sodium Deficiency is Hyper-hydration, people drinking four or five or six litres of water a day stripping the Sodium at a greater rate than they can actually hold it. The other cause is Adrenal Exhaustion, and that’s a more common thing because, what happens with Adrenal Exhaustion you get a lot of other Inflammatory conditions, and you might get this disorder. The way they treat this, and I don’t know how to say Dupuytren’s Disorder, but we’ll just make something up. We’ll call it…
Jeff: Dupuytren’s Disease.
Matt: Yeah, so do that, and I’ll just point at you every time I want you to say it. So, the way they treat…
Matt: …is they use Anti-Inflammatories and that sort of stuff, which your Adrenal Glands should be making anyway. And, at the same time, those same Anti-Inflammatories, mainly Cortisol, made from your Adrenal Gland is our most powerful Anti-Inflammatory in the body and that’s what also holds Salt into our body.
Jeff: Oh, wow!
Matt: The other thing the Cortisol from the Adrenal Gland does is it regulates your mood, and without it you get Depression.
Jeff: There you go, you’ve got the whole box and dice.
Matt: But, you get a Depression that’s borne from Fatigue not from Anxiety. So, you get a Depression with Hypersomnia where you lose Motivation, you stop seeing the joy in life, you wake up in the morning and you just want to go back to bed. What’s interesting about Pristiq as an Antidepressant is that it works different to other Antidepressants, where it preserves Serotonin, which is the sleepy chemical. And, classically, if someone gets Depression with Adrenal Exhaustion it’s usually because they’ve got too much Serotonin, which is why they want to sleep all the time, which is why they don’t want to go out and do anything. They’ve got the same chemical you get when you’re about to fall asleep when you’ve drunk too much or after a shag, so you just lose all your Motivation and Drive. But, Pristiq works differently, because it does preserve Serotonin, like other Antidepressants, but it also preserves nor-adrenaline which is the chemical that normally wakes you up and gives you a bit of energy. So, typically, they get onto Pristiq because they were put onto a classic Serotonin preserving Antidepressant and that just made them worse and then they go, “Well, try this one,” and then they’re on the Pristiq, and they might feel better on this one because they’re preserving nor-adrenaline, which offsets the Adrenal Exhaustion.
So, the way I would treat it is actually by trying to Increase the Adrenal Cortisol production. Now, normally first thing in the morning the Adrenal Gland pumps out a heap of Cortisol and that wakes you up, gives you plenty of energy. It’s also an Anti-Inflammatory, takes away all your aches and pains, lubricates your joints and allows your fingers to move, that sort of thing.
So, what I would be doing is probably using—and this doesn’t interact with the medication, but again, bloody–that disclaimer thing, double check with your pharmacist and doctor and that sort of stuff, but in this situation, I would use the CORT RX of a relatively low dose of one capsule three times a day, but a low dose frequently, because I want a steady blood level of the Anti-Inflammatories and that sort of stuff.
Then, what I would actually do is buy—I use a product, it’s an Adrenal Gland extract, I buy it from a company called Thorne, but there are so many different companies, but I actually use 150 milligrams of Adrenal Gland extract and I do about 300 milligrams for breakfast and then 150 milligrams around lunch time. And, what we do is, we try to recreate that Cortisol surge the whole time we’re using the CORT RX to take the burden off the body. And, that’s how you can rebuild that Adrenal Function.
And, the other thing that could be really cool for this is Liquorice Root. It makes a beautiful tea. Liquorice Root will hold that Sodium into the body, and it mimics Cortisol. So, it will float around pretending to be Cortisol sending a message back to the Adrenals saying, “Hey, I’ve got it covered, you just focus on Rebuilding.”
Jeff: Wow! That’s cool.
Matt: But, in the meantime it holds that extra Sodium into the body, and if you can hold that extra Sodium into the body—if you’ve got a problem where this thing is cramping and the cramp causes the Calcium build up it might actually start to free things up.
Jeff: Would you recommend—I see rock salt there; would you recommend the Celtic Sea Salt.
Matt: Oh yeah, whatever.
Jeff: It doesn’t matter?
Matt: Nah, it doesn’t matter. I mean the Celtic Sea Salt is better, but we’re talking about Sodium, mainly the others are loaded up with extra Magnesium, Potassium, Iodine, that sort of stuff.
Use the DRAGONS BREATH on the palm of the hand as well, because it will help to displace the Calcium. You can even buy Magnesium Chloride and add it to water and massage that into your hand as well. But, DRAGONS BREATH will work.
Jeff: We might, actually, throw Beck out everything that she needs that we supply, so that’s the DRAGONS BREATH, the CORT RX.
Matt: Oh, that’s a good idea.
Jeff: Is there anything else, Matt, that we can give, that you’d recommend that she uses?
Matt: Beck needs BLOCK E3.
Jeff: Well we’ll throw it out for Beck as well, too.
Matt: Yeah, do that.
Jeff: So, for your mum we’ll get the CORT RX and the DRAGONS BREATH.
Matt: And, the Trophy for Mum.
Jeff: And, the Trophy.
Matt: Oh, the other question was, was there anything for the ASD, which is the Asperger’s Spectrum Disorder, or the Autistic Spectrum Disorder, I’m not sure.
Jeff: Asperger’s, yeah.
Matt: I was in denial and said I was somewhere on the Artistic Spectrum, I thought they’d said to me.
Jeff: Because, you were diagnosed with that, weren’t you, Matt?
Matt: Oh probably, or just being an arsehole.
Matt: I think that’s what they diagnosed me with.
Jeff: Arsehole Spectrum Disorder?
Matt: Yeah, that’s the ASD. But, the ALPHA VENUS is a very interesting product. The Broccoli Sprouts activate this NRF2 gene. The NRF2 gene is possibly one of the most exciting developments for everything from Alzheimer’s, Dementia through to Autism and Asperger’s. There’s a particular gene that you can activate with these Broccoli compounds that trigger all of the Resilient Antioxidant Defence Mechanisms and help with significant changes for the Behaviour and the Brain Function. So, I would be using something like the ALPHA VENUS, or just have a look at what’s in ALPHA VENUS and try to incorporate that into the diet.
Jeff: Well, we’ll send her an ALPHA VENUS.
Matt: Yeah. So, those foods that are in there, load up on the Broccoli, anything in the Brassica, heaps of Kelp, heaps of Rosemary. I’m not sure how young this kid is, or what the dose…
Jeff: Good point. We’ll send it and if he’s over the age of 15 he can use it, no problem at all.
Jeff: Also Beck, go back and have a listen to the last podcast…
Matt: Beck will snavvil it if he can’t use it anyway.
Jeff: I’m sure she will. But, listen to the last podcast we did, Beck, because we talk a lot about the NRF2 there, there’s a some really exciting stuff in regards Asperger’s, Autism, ADHD, all that with regards to the brain.
Matt: Yeah. And, the Rosemary itself is fantastic as well, and that’s an NRF2 activator.
Jeff: Alright Beck, I hope that helps. Say g’day to your mum for us.
Okay, what have we got here, Matt? We’ve got one more.
This is from Alan.
Jeff: Steve: “I have something a little different for you guys that may be of interest to your fellow female competitors and women in general. I’ve been on the pill, Yasmin, going on 10 years now, and I’d really like to come off it. However, I have some concerns and uncertainties about how this will affect my body in terms of it’s Hormonal Status, Body Composition, Lean Mass and Body Fat, also Behaviour and Mood.
This particular pill has also been given a pretty bad rap recently and there doesn’t seem to be much info out there about this sort of thing. The research I have done found numerous stories about the side effects that other women have experienced about coming off a pill, such as a complete Mood Change, Personality Shifts, Depression to the point of requiring Antidepressants, Anxiety, Weight Loss, Weight Gain, Acne, Insomnia, to mention a few.
I compete as a fitness model and eat and train to maintain a healthy balanced Hormonal Status among many other things. I eat extremely well and supplement with Adaptogenic Herbs, ALPHA VENUS, T432 PLUS, CORT RX, and I also use the ATP Transdermal Products because, hands down, they are the best. I like to keep it as holistic as possible too.
So, I’m hoping you can help me and fill me in on what’s really going on with the body once you take away these synthetic Hormones. Is there any way to counteract the side effects, if any, and if so, how can this be done?
I feel like coming off the pill might compromise my physique which requires constant hard work and serious dedication, not to mention the side effects I listed earlier. So, obviously I would really like to avoid this if possible. I have read a story online about a woman who sought help from a Naturopath to Detox from the pill and her outcome was incredibly amazing. So, no pressure, Matt. But, seriously, I really appreciate the advice you have to offer, I love your products, and I refer to you guys as The Game Changers because I can’t wait to see what’s in store for ATP.
Cheers Allen, and in inverted commas, not Allan spelt with an A.
Matt: Jeff can’t speak.
Jeff: I can’t say Allan or Ellen, so it’s just Steve.
Matt: It’s going to be Steve.
Jeff: Thanks Steve.
Matt: Thanks Steve?
Jeff: Can you help Steve?
Matt: Yeah, of course. What you’ll find is…
Jeff: It’s multifaceted.
Matt: Yeah, yeah. It is, for sure. What a lot of people don’t realise as well is the reason you go on the pill…
Jeff: Is not to get pregnant.
Matt: Well, that’s what it’s designed for, but they don’t use it that way. So, for example, some people have Hormonal Dysfunction, they have Hormonal imbalance, whether it’s Structural or Biochemical, but they have Pain or Bleeding or Mood Changes, or whatever, and that’s what they get put on the pill for. What the pill does, it kind of takes over your Hormonal production and just delays the inevitable. So, if you haven’t fixed the cause of the problem that they prescribed the pill for initially, and you come off it, then those problems have continued to get worse in the background, so when you come off it you have an exaggerated effect of what you had previously. But, if you’re on it for contraception and that sort of stuff that’s different. So, we don’t know Steve’s background reasons for being on the pill.
But, I’ll tell you what’s really cool to talk about is the stuff that Steve brought up about the side effects and what happens when you come off it. There are some massive problems that links in with Yasmin with blood clots and all these sorts of things while they’re on it. And, what’s interesting about this particular pill is, it increases the production of this 16alpha-hydroxyestrone, and that’s a very strong and active form of Estrogen. But, what it does, it tells your body to make more of this particular type of Estrogen but it also only makes a certain amount of it. So, it makes the bad Estrogen but it keeps it relatively low, that way you get a little bit of Hormone that has an exaggerated effect, and that’s one of the ways it works for Contraception, by sending a message back saying, “Don’t bother making any more.”
Jeff: Yasmin, that’s not the mini pill, is it?
Matt: I don’t remember what they call the bloody things.
Jeff: Yeah, anyway go on.
Matt: So, Yasmin makes this 16alpha-hydroxyestrone, but while you’re on the Yasmin it keeps the levels of that Hormone relatively low. When you come off it, you’re still making the dodgy 16alpha-hydroxyestrone, it’s just all of a sudden you make a heap of it, there’s nothing keeping a cap on it, so your body goes and makes a lot.
Matt: And, then the problem is, you get exaggerated effects of Estrogen, so the 16alpha-hydroxyestrone holds Fat, holds Fluid, aggravates the Clots, that’s why a side effect of it is a Clot anyway, when you’re on it, but you get more predisposition to Clots, Varicose Veins, DVTs when come off it as well.
Matt: So, it was the cause of the problem but also they almost market it as a treatment for the problem because you can’t come off it because of these. 16alpha-hydroxyestrone exaggerates and amplifies Stress and Worry, and Panic, and that does all the brain things, it causes Insulin problems. So yeah, of course, it screws with physical body shape and mental activity.
The key is, when you come off Yasmin is to reboot the Liver Pathways and send that 16alpha-hydroxyestrone down the other Pathway, and make 2alphahydroxy and ultimately the 2methoxyestrone, which has an Antiestrogen effect. So, what that basically means is, when you come off the Yasmin if you don’t reboot the Pathways, if you don’t switch off the Pathways that Yasmin switched on, then you’re going to get worse.
So, the key is, ALPHA VENUS does it. ALPHA VENUS will help convert 16Alpha down to the 2Alpha, and then, what I was saying to Beck before, stack it with B6, B12, Folic Acid. So, take a good multivitamin, take the ALPHA VENUS. You can start that for a full month before you come off Yasmin, if you want, make sure the stuff’s in your system, it’s already going to start switching it over, and you’ll feel different anyway if you had any Premenstrual Dramas while on the Yasmin they’ll disappear anyway.
Jeff: Yeah, it’s amazing.
Matt: Then, you just take out the pill and you’re rebooting the Pathways. That’s about all you really need to do, the only other thing I tell people to do is make sure you’ve got adequate Fibre and that sort of stuff, and also make sure, while on the Yasmin, that 16alpha-hydroxyestrone hasn’t fed and increased your colonies of Bad Bacteria and Fungi and Candida that may be keeping the process happening. So, if you’ve got Thrush and Urinary Tract Infections and that from the Yasmin, kill that stuff off first, because otherwise you go to fix the Pathways and then those dodgy bugs in the Gut will just go through and thwart our plan.
Matt: So, that’s it, ALPHA VENUS, B6, B12, Folate, strip that 16alpha-hydroxyestrone back to the 2Alpha. I mean you can measure that too, now. You can go to the doctor and request a Urine Test for the ratios between the 2Alpha and 16Alpha and it will give you a bit of an indication if you’re high risk.
Jeff: And, just quickly, for Steve again, what is the amount that she needs for the B12 and the…
Matt: So, about 1000 micrograms of Folic Acid, 1000 micrograms of B12, and around about 30 to 50 milligrams, something like that.
Jeff: 30 to 50 milligrams?
Matt: Yeah, milligrams. And, then you go with the ALPHA VENUS, take two capsules twice a day, and that should reboot it.
Jeff: Alright cool. Thanks Matt. Anything else for Steve?
Jeff: Well thanks for your question, hopefully that helps.
Matt, last word?
Matt: Oh shit.
Jeff: No, he’s got nothing. And, nobody’s sending you any.
Matt: I keep forgetting too, to even think about it.
Jeff: Well, thanks everyone for listening. Menopause, Andropause, a little bit on Testosterone, some FAQs. Keep the FAQs coming because they’re great, we’re learning a lot and we’re able to help a lot of people, and I’m sure there’s a lot of people that have got issues that by listening to them they can relate to as well, so keep them coming.
And, Matt, we’ll see you next week.
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