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ATP Science Episode 68 – Diabetes
Welcome to the ATP Project, Episode 68 – Diabetes and Insulin Control for Health, Fat Loss and Muscle.
• Diabetes and the associated Hormone Pathways
• This podcast includes great info for Fat Loss and Muscle Building.
o Hernia Recovery [00:39:22]
o Estrogen & Progesterone Ration side effects [00:53:31]
o ATP Supplements and Pregnancy [00:49:14]
o Shaping Muscle Mass & Mitochondrial Density [00:57:37]
o Fungal Overgrowth and how to kill it. [01:03:50]
Welcome to the ATP Project, you’re with your hosts Matt and Jeff.
Matt: What did you call me?
Jeff: Mate, a lot of people have got it. And, what’s interesting, just having a look around the different states with regards to Diabetes, we know that it’s a major health risk now, there seems to be a lot of people dying from it, and worse–worse than dying?
Matt: Having to public speak about it.
Jeff: Exactly. Touché Matt, that’s good. But, worse than that—well, no nothing’s worse than that, but amputations and all sorts of other horrible things happening as well: Blindness is obviously associated with it—there are a whole host of complications with Diabetes, it’s not just about having to inject yourself with Insulin.
Matt: Yeah, that’s right.
Jeff: Before we get into some of the statistics, because when you think Diabetes, and I did, I thought the United States has got to be on top, and it’s close, about 11% of the population between the ages of 20 and 79 have it. Australia is currently sitting just below 5%, which I was quite surprised at, Britain is around 6% or thereabouts, but it’s actually a lot of the islands, like Palau is like 25%, I think.
Jeff: So, one in every four people—Papua New Guinea is like 18%, so weird places where you’d think relatively these people would be healthy but they’re getting Diabetes.
Matt: It’s interesting too, because they look at the risk factors for Diabetes and it’s always Obesity, they always talk about Obesity, Obesity and that sort of stuff. But, especially through some of those Asian places you mentioned where the Obesity is not as prevalent as it is in Australia and America and the UK yet their rates of Diabetes are so damn high, so it makes you wonder.
Jeff: Yeah. And, in some places like Saudi Araba 20% –
Matt: What form of Diabetes are you looking at with those stats? Is that Type 1 or 2?
Jeff: That’s overall, that’s combined.
Matt: Just Diabetes in general?
Jeff: Yeah, that’s right. So, probably Type 2 is the one we’re more interested in.
Matt: In most populations, you’ll find less than 10% of Diabetic population will be Type 1.
Jeff: So, can we talk about that then, Matt? What is Diabetes, just quickly, to give a recap for those that don’t know and should know, and it’s probably something that everybody should educate themselves about. And, secondly, what is the difference between Type 1 and Type 2?
Matt: Basically, Diabetes is high Blood Sugar, that’s what it is. Type 1 Diabetes is an Autoimmune condition where the Immune System eats away the cells in the Pancreas that make Insulin and in Type 1 Diabetes they don’t have Insulin so therefore they can’t take Sugar out of their Blood. So, that’s Insulin’s job in the body. To simplify the job of Insulin, of which there are many functions, but it’s number one job is to take Sugar out of the Blood. In Type 1 Diabetes their body is not capable of making Insulin therefore they can’t take the Sugar out of their Blood.
Jeff: So, that’s the differences between Type 1 and Type 2.
Matt: Well, I only talked about Type 1.
Jeff: Oh, well what’s Type 2?
Matt: Type 2 is when the Insulin doesn’t work, where you acquire an Insulin Resistance, so you’ve either got a heap of Insulin that does nothing, or your Pancreas is buggered and it can’t pump out enough Insulin, but it’s an Insulin Resistance Syndrome, Type 2.
Jeff: So, the people who are listening who have Type 1, Matt, what is your advice to them? To be fair to those people it’s probably Type 2 Diabetes that is one that we can address the most and is the one that is the epidemic.
Matt: Yeah, well at this stage we don’t have a way of rebuilding Beta Islet Cells of the Pancreas, you can’t go and replenish those Cells that have been eaten away and destroyed. So, with Type 1 Diabetes the initial treatment, if you know you’re about to get it or if you’re in the process of Autoimmunity there are some things you can do to reduce the damage to the Pancreas, such as big doses of Vitamin B3 have been used to preserve the Pancreatic Cells. Other typical treatments to control the Autoimmunity—they think there’s a big link in there with Dairy as well in infants where they have an Autoimmunity based on Casein, Dairy Protein, that triggers an Autoimmune reaction to the Pancreas.
Jeff: So, they need to investigate that a bit more?
Matt: Yeah, so look into those sorts of things. But, if you’ve been diagnosed with Type 1 Diabetes you’re at that stage now where it becomes a management issue, and what you’re doing there is you’re measuring your Blood Sugar and using Insulin to keep your Blood Sugar in a proper window, and the rest of the time you’re putting in a bit of safety net in case you lose the ability to monitor or control your Blood Sugar and you Blood Sugar spikes and gets too high. If your Sugar gets too high in the Blood, it starts to damage all the Tissues and everything. So, what the body does is it takes that Sugar out of the Blood, converts it into a thing called Sorbitol, the Sorbitol then gets absorbed inside certain Cells of the body, so there are particular Enzymes that convert Glucose through to Sorbitol and they’re only found in certain Cells, they’re found in the Cells of the Eyes, at the end of the Nerves and in the Kidneys, and in those particular Cells they can convert Glucose to Sorbitol, the Sorbitol goes inside the Cell thereby dropping Blood Sugar. The problem is that Sorbitol is highly water soluble, and so when it goes inside a Cell and builds up all this water rushes inside the Cell and then the Cell puffs right up and then pops, and then that Cell is damaged and that’s how you get the long-term complications of the Numb feet, the Blindness, the Kidney damage and that sort of thing.
So, people with Type 1 Diabetes is they monitor their own Blood Sugar and foods and training and all that sort of stuff, and then we put in some safety net things like, from memory, Bilberry. Bilberry is one of my favourite Herbs for Type 1 Diabetics to stop their Eye damage and it also protects the Kidneys and the Feet. The other one is Hawthorn Berries is another good one, so Bilberry and Hawthorn I used to make up liquid tonics of that and these people smack it down. Lipoic Acid is another one that’s really good.
Jeff: What does Lipoic Acid do? That helps with shuffling Sugars doesn’t it?
Matt: Lipoic Acid does a lot of thing in regards to improving Insulin sensitivity, for example, for Type 2 Diabetics Lipoic Acid is really handy to improve Insulin sensitivity, we use about a 200 milligram does three times a day, and it can drop their Blood Sugar by about 30%, so it’s actually a pretty powerful little tool.
Jeff: You mentioned Diet and Exercise, so I’m assuming you’re saying Low GI Carbohydrate combining Protein and those sorts of things together?
Matt: It’s a weird thing, once you’ve got Type 1 Diabetes these people are at just as high risk of going low Blood Sugar as they are high Blood Sugar.
Jeff: Is this where the guy collapses in the playground and you throw the jelly bean down his throat?
Matt: Exactly, yeah. So, this is the thing, with Type 1 Diabetics if they’ve got their Insulin in and the Insulin works, or if they go and Exercise and that sucks the Sugar in, they can get a Hypo, a Hypoglycaemia and then in that case they need some Sugar to function again.
Jeff: Don’t go too low?
Matt: Yeah. Otherwise they can be predisposed to going too high, so they’ve got to monitor their Blood Sugar levels in response to Dietary and Exercise changes, and they will work out what works for them and all that, and work it that way. So, that’s in Type 1 Diabetics, and a lot of it, as I said, is management and just dealing with the consequences of having Blood Sugar that can go all over the shop.
Jeff: It’s interesting. That’s probably why a lot of people talk about Stem Cell research. Apparently, there is some unbelievable Stem Cell research that’s coming from the umbilical cord of the—I mean it takes away the ethical debate where a lot of people are like, “No, you can’t do that.” You can even take out your own Stem Cells and they’re using those now, so there is some really cool stuff being done.
Matt: When you’re having a baby now, I think it’s 10 or $15,000 and they can take the umbilical cord and freeze it and preserve the Stem Cells in case your children need access to their own Stem Cells in the future.
Jeff: It’s awesome. Again, I understand there’s a whole debate, and a lot of people are skewed towards foetuses and things like that, and that is a very morally questionable area.
Jeff: But, if there are other ways that you can bypass that to get everybody on board, that sort of research and science is fantastic.
Matt: Oh, yeah it would be cool, a lot of things go with it. So, that’s about Type 1 Diabetes and that’s about 10% of the Diabetic population. Apart from the damage to the Cells at the periphery, the other thing that can kill a Type 1 Diabetic that they need to keep an eye on—and, this is an interesting thing for our typical listeners that are doing these Fat Loss Diets and everything—what kills the majority of people with Type 1 Diabetes is Keto Acidosis. So, because their Blood Sugar is struggling to get in and out of Cells they’re predisposed to using Fat as a source of fuel with a by-product of Ketones being produced, and if they get too many Ketones made they get a condition called Ketoacidosis that will eventually kill you.
The reason why I’m talking about it is because a Low Carb Diet, people who are on the Low Carb Keto style Diets are trying to build up as many Ketones as possible, and they’re actually going to the pharmacies usually and buying the Ketone measuring sticks for Diabetics so they can fist pump the air when they get a high reading on these things to show that they’re Burning Fat, while the Diabetics are supposed to be using these sticks and when they get a high reading they’re like, “Oh no.” So, it’s interesting to see that some people think, “Oh yeah, we can go Low Carb, High Fat, and then supplement with extra Ketones,” and that makes them healthy, but it’s like, “Mm.”
Jeff: It’s strange, isn’t it? If you do happen to be like that, it’s a simple case of putting more Carbohydrates into the Diet, so that the body switches fuel sources?
Matt: Well, we’re talking about typical people, but Diabetics don’t have that luxury, that’s the problem, so they’ve got to be careful.
Jeff: So, what do they do?
Matt: They’ve got to make sure they’re not eating extra Ketones and that sort of stuff that can contribute to the Ketones and then they’ve just got to get their Blood Sugar and Exercise and that under control again to try to get a bit more balance and structure.
Jeff: It sounds tough.
Matt: Yeah, it is. It’s a challenging one. Type 2 Diabetes there’s a lot more research on it, there’s a lot more information on it, because there’s a lot more of it, it’s more of a management issue, and if we get the pre-Diabetes signals or if we see that you’re on the road to getting Type 2 Diabetes then they can start implementing changes and prevent it. Where Type 1 it’s often a sudden sort of thing that happens, or it happens as a child.
Type 2 Diabetes that’s what we call an Insulin Resistance, so that’s when the Pancreas is pumping out the Insulin but the Insulin is just not working, and then the Sugar doesn’t change. So, interestingly, the driving force behind the Insulin Resistance is different in every person, so in some people it’s because of Obesity because they’ve got too much Fat putting too much Fat in their Bloodstream and that gets in the way with Insulin working, or the Triglycerides are glugging up everything. Other people who don’t have enough Muscle, and because they don’t have enough Muscle they’ve got nowhere to put the Sugar.
An interesting feature that most people talk about, because they just keep linking Type 2 Diabetes and Obesity and they’re basically saying, “The problem is you’ve got too much Fat and that’s what causes Diabetes.” But, what’s really fascinating about it is it’s almost as if the Insulin Resistance is what causes the Obesity, so instead of saying Obesity causes Insulin Resistance it may actually be the other way around. Because, Fat Cells don’t actually get Insulin Resistance, so the Fat Cells will always take the Sugar on, this is the problem. It’s actually the Muscle that becomes Insulin Resistant.
Jeff: How does it become Insulin Resistant?
Matt: Typically, Inflammation, damage to the Insulin Receptors, a lot of Toxins and that sort of stuff. Nutrient Deficiencies is very common, just basic not enough good Omega 3, too much Omega 6, Deficiencies of things like B Vitamins, Zinc, Chromium, all that sort of stuff, and like I said, it could be different in every person, there are a lot of different reasons, there’s also those Genetic links. So, it’s the Muscle that becomes Resistant to Insulin first, which means the Muscle is not only Resistant to the ability of the Insulin to put the Sugar into the Muscle to be used as source of fuel, but it’s also Resistant to such things as Insulin like Growth Factor. So, the IGF-1 that stimulates Muscle growth in response to Exercise and Calories and things like that, you’re Resistant to that. So, before you go and get crazy amounts of—the only reason why the Sugar is getting shoved over into your Fat Cells is because it can’t go into your Muscle.
Jeff: So, you conceive this as quite a vicious circle?
Matt: Well, the problem is if they going through and saying that the problem is that you’re just too Fat—Obesity can be caused by Insulin Resistance. So, the more likely scenario is that you become Insulin Resistant for a variety of reasons, either your body sees too much Insulin because you eat too much Sugar, your Insulin stops working because of Inflammation, Toxic Exposure, Nutrient Deficiencies, Genetics, or whatever…
Jeff: It stops working into the Muscle or stops working from the Pancreas?
Matt: Stops working in the Muscle. We’re talking about Type 2 Diabetes, forget about the Pancreas, it’s working as hard as it can.
Jeff: It’s doing alright?
Matt: Yeah. It’s just that the Sugar can’t get out of the Bloodstream because the Insulin cannot drive it into the Muscle.
Jeff: So, that is the sticky gate they talk about?
Matt: So then, you can’t keep your Sugar in the Blood for long so what it does is it goes, “Well shove it over into the Fat Cells, they’ll always take it,” and then the Fat Cells have got to work through a process of converting the Sugar to Fat then liberating back Fat into the Bloodstream, it causes a vicious cycle because as the Fat comes back out of the Fat Cells it lets Triglycerides into the Bloodstream, that causes Insulin Resistance in Muscle.
Jeff: Bloody hell.
Matt: So, what ends up happening is, with Resistance to Insulin-Like Growth Factor, it’s Resistance of the ability to drive Sugar into your Muscles; you are Resistant to Muscle Growth.
Jeff: Yeah, I was going to say you’re into Atrophy.
Matt: So, you can’t build much Muscle. If you look at Muscle as a reservoir for Sugar—if your Sugar goes too high your Muscle takes it up, but if you’re not building Muscle, you’re not holding Muscle, you’re not capable of converting Sugar to Glycogens and holding Sugar into the Muscle, and you Exercise, you work and your Muscle gets smaller and smaller and smaller and Catabolic, and your body is constantly preserving Fat Cells, and the next thing you know they’re going, “Well, there’s an association between Obesity and Diabetes.”
What typically happens before you get diagnosed with Diabetes you’re diagnosed with some sort of Insulin Resistance. So, as they go through a phase of Insulin Resistance it’s the Insulin Resistance that causes the Sarcopenic Obesity, which is the Obesity based on no Muscle, so your ratios of Muscle and Fat are out of whack because you’ve got no Muscle, and then what eventually happens is you get Fat, and then they say, “Now, you’ve got Diabetes.”
Jeff: So, one of the best things you can do for Diabetics to ward that off is weight training, resistance training?
Matt: Yeah, exactly.
Jeff: Looking after your Muscle Cell.
Matt: Yeah. Because, to get Sugar out of your Bloodstream, typically, it requires Insulin binding to an antenna, that antenna sends a cascade of signals that then opens a door to allow Sugar through. Exercise can bypass that requirement for the Insulin binding to a Receptor, because as Exercise depletes Glycogen reserves it activates these GLUT4 Transporters that can suck Sugar in to replenish the Glycogen without the need for Insulin. So, this is the big key, people can work on the timing of their intake of Carbohydrates in response to Exercise they can replenish Muscle Glycogen and all that sort of stuff and preserve Muscle and build Muscle without causing spikes in Blood Sugar.
Jeff: It would be interesting, because obviously, a large section of our listeners, Matt, are into building Muscle, and there are some tricks here that they can learn about Sugar, GLUT4, Insulin and things like that to improve Muscle Growth.
Matt: And, Insulin Sensitivity. An important message for other people out there that aren’t Diabetics that are weight trainers and things like that is, Insulin Sensitivity is not just talking about Blood Sugar, it’s also talking about Insulin-Like Growth Factor and the ability for all these Calories and everything to stimulate Muscle Growth.
Jeff: And, that’s part of the IGF-1 is it?
Jeff: And, IGF-2 is Bone and that sort of stuff, isn’t it, but IGF-1 is the one we’re talking about. I know a lot of body builders back in the day, and probably to this day, inject it because it’s so beneficial for improving Muscle.
Matt: But, if you have Insulin Resistance it does not work.
Matt: Yeah, so that’s the thing. Now, that’s when we’re talking about mainly Impaired Glucose Tolerance, so you know when your wife is pregnant and they make them do the Glucose Tolerance tests?
Matt: They’re looking at how your body Blood Sugar responds to intake of Carbohydrate throughout the day. The other way they diagnose Type 2 Diabetes is Impaired Fasting Glucose, so when you haven’t eaten for 12 hours what are your Blood Sugar levels? So, by the time you’re getting Impaired Glucose Tolerance, so you’re getting Insulin Resistance, but that can be transient, it can be temporary, so your Blood Sugar—and, then it corrects itself after a short period of time. To get the diagnosis of Diabetes you have to start getting the Impaired Fasting Glucose meaning that you have to start waking up in the morning with really high Blood Sugar.
Matt: Now, think about that, if you haven’t eaten for 12 hours and you’ve got high Blood Sugar where does that come from? Especially when a lot of these people are measuring their Blood Sugar at night, they have their evening meal, their Blood Sugar is not crazy high at night, but somehow, without eating for over 12 hours, they wake up in the morning with crazy high Blood Sugar levels; they haven’t eaten though.
Jeff: How does that even happen?
Matt: What happens in that case is that talks more about the Liver, the ability of the Liver. So, your Liver gets seven litres of Blood every hour, so your Liver is a really cool place, we have a whole heap of little antennas and stuff like that to measure the Blood, so your Liver is covered in all these little antennas and as the Blood runs through your Liver is measuring all this stuff in the Blood so it knows what it needs to do, “Do I need to take Toxins out? Do I need to add Nutrients in?” that sort of thing. So, what happens in this situation is the Liver—and, it stores Glycogen remember, so the Liver holds Sugar and if your Blood Sugar drops the Liver pumps that Sugar out to fill up your Bloodstream because it can do that really quickly, really effectively.
So, with poor fasting Blood Sugar these people wake up in the morning with really high Sugar levels but they haven’t eaten for 12 hours. What actually happens is, while they’re asleep their Blood is running through their Liver, the antennas on the Liver are Insulin Resistant. If you’ve got Insulin Resistance in your Liver then these antennas aren’t capable of measuring the Sugar in the Blood, the Sugar is not telling the Liver there’s Sugar here, so the Liver thinks you’ve got no Sugar because the Liver is inflamed, the Liver is damaged, the Liver is usually Fatty and all that sort of stuff in these situations. So, then what happens is the antennas in the Liver aren’t working so the signals are saying, “There’s no activation of Sugar on these receptors and these antennas, so therefore this person must have no Sugar in their Blood, therefore let’s pump a heap out.”
Jeff: So, Matt, is that why, even for Fat Loss, if you Detoxify the Liver the body is better at evening out Blood Sugar levels?
Jeff: So, Fatty Liver is an enemy, as is Liver disease, and Alcohol as well too, so obviously, these are all sorts of cascading events in the Liver.
Matt: And, you’ll see in Type 2 Diabetes it’s often associated with Fatty Liver, it’s often associated with Liver Inflammation or a lot of Visceral Fat, so a lot of Fat in and around their internal organs which just gets in the way of all the signals going through. If you get too much Fat in your Liver and too much Triglycerides in your Blood that’s what gets in the way of the antennas working, and the Blood has got too much Fat in it for the antennas to measure the Sugar, so then the Liver thinks, “I’ve got no Sugar, I better pump some out.” So, in that situation they get really high Blood Sugar, these people are then constantly trying to change the way they’re eating thinking that’s going to fix their morning Blood Sugar but it’s actually got bugger all to do with what they’ve eaten, it’s more to do with the way their Liver is working.
So, in that sort of situation there are things we can use to block the Liver from releasing Sugar, that’s one of the ways AMP works and that sort of stuff as well, through the PPAR Receptors, so those Essential Fatty Acids that go through and interact with certain receptors in the Liver can tell the Liver, “No, you don’t need to release Sugar, we want to keep releasing that Fat, we want to keep Burning Fat instead.” Because, somewhere through the night your Liver is supposed to switch over to Fat Burning but in this situation, it just keeps pumping Sugar out and you’re Burning Sugar all the time.
Jeff: So, the PPAR Receptors working on in the Liver, so someone who has Fatty Liver is either pre-Diabetic or Diabetic, or they’re overweight and they’re worried about that situation, utilising PPAR modifiers to the Liver is going to be a must for them?
Matt: Yeah, absolutely.
Jeff: And, what is PPAR again? I know we’ve got a whole podcast we did on it, but just a quick recap.
Matt: They’re a group of receptors that help to regulate the body’s hierarchy of what fuel we’re going to use, and if you modulate the receptors properly you can tell the body to use Fat as a primary source of fuel.
Jeff: And, because the Sugar is already stored in the Liver it’s not like the Sugar is going to be floating around causing damage to the Eyes or the Extremities or the Kidneys, we just want to stop it from releasing it.
Matt: Yeah, exactly.
Jeff: So, a combination of Diet, PPAR Receptor modifiers…
Matt: Then, things that work on the Inflammation through the Liver. Gymnema Sylvestre is an interesting Herb, Gymnema is a very powerful Herb that we use to numb sweet taste buds of the tongue, Gymnema Sylvester
Matt: I don’t know how to say it, that’s how I say it.
Jeff: I call it Salvestre.
Matt: Yeah, you can do what you want, I just read this shit too.
Jeff: I don’t know if either of us is right.
Matt: Well, it doesn’t matter, we’re making it up.
Jeff: Anyway, you know what we’re talking about.
Matt: That’s the good thing about podcasts, “Yeah, I agree with you.” So yeah, Gymnema is really cool because it seems to be very good at controlling Fasting Blood Sugar and there’s a lot of research on how it actually works via the Liver to do that. The other way of doing it is to put in things that block the ability of the Liver to release Sugar, that’s where high doses of Biotin and Berberine and that sort of stuff work. People take Metformin, that’s a drug for Diabetics, that’s supposed to work on Insulin Sensitivity, they’re starting to give it now to people with Polycystic Ovarian Syndrome and all sorts of other Insulin Resistant syndromes. One of the ways they found out it works is it actually stops the Liver from releasing Sugar so it keeps the Fasting Blood Sugar down that way not actually by improving Insulin as they thought. So, you can stop the Liver from releasing Sugar and that will drop the Blood Sugar in the morning as well, and tells the body to Burn Fat.
Matt: So, the main thing with Type 2 Diabetes is looking at things that improve Insulin Sensitivity. It’s quite funny, everyone talks about Chromium and that sort of stuff.
Jeff: Yeah, Chromium Picolinate, Chromium Polynicotinate.
Matt: It’s interesting Chromium. With Chromium, and I’m not sure exactly which one came first, but they discovered this thing in Brewer’s Yeast called GTF which is Glucose Tolerance Factor. You’ve been in the industry for a while, do you remember 10 or 20 years ago they used to have all these GTF pills, you used to be able to buy Glucose Tolerance Factor?
Jeff: I don’t remember it, no.
Matt: It was the first thing you did as a Naturopath was, you’d make sure they had the Glucose Tolerance Factor. What they found was there is a complex group of Minerals and that sort of stuff that is found in Nature that when we eat them they work together as a combination compound that then helps Insulin Sensitivity. For example, the studies on Glucose Tolerance Factor show that if you combine Glucose Tolerance Factor with Insulin it makes Insulin work somewhere between two to two and a half times as effective.
Matt: Yeah, so massive amounts, but more importantly these are Essential Nutrients, and if you’re deficient in the Nutrients that are necessary for the creation of the Glucose Tolerance Factor then your Insulin doesn’t work, that’s one of the main Nutrients. So, Glucose Tolerance Factor is Chromium mixed with Nicotinic Acid, I think it’s one Chromium molecule to two B3s and then a couple of Amino Acids, which I think are Glycine, Cysteine and Glutamic Acid. So, that’s what Glucose Tolerance Factor is.
Jeff: People who are pre-Diabetic and Diabetics are saying, “I want this,” and I can hear body builders going, “I want this now.”
Matt: Yeah, and it’s out of Brewer’s Yeast. That’s where it was originally found and then isolated and extracted from Brewer’s Yeast, and then they did all this research on it and found it’s a natural component in us, it’s a natural component in a lot of plants and other things like that.
Jeff: Now, in the sports industry, obviously, we learn a lot from disease states and how to manipulate the body and get things working. Insulin we know is more Anabolic even than Testosterone, and therefore a lot of guys, post training, will take a huge dose of simple Sugars not only to reload Glucose and Glycogen, but also to drive Insulin which then helps them become Anabolic, taking Protein, building Muscles, Creatine and that sort of stuff as well. But, I have never heard of what you just talked about. Why isn’t this everywhere? Because, a lot of people…
Matt: Because it’s found in Nature.
Jeff: But, surely…
Matt: You just said it yourself.
Jeff: What do you mean?
Matt: “I’ve heard of Chromium Nicotinate.” So, all these people don’t want to go and say Glucose Tolerance Factor is found in Nature and we all need it, and if you go and buy Brewer’s Yeast which is Saccharomyces Boulardii that you can buy for five bucks for a horrible yeasty bag of something that lasts you for ages, they don’t want that. What they do want to say, and like I said, Glucose Tolerance Factor is Chromium, B3, Cysteine, Glutamic Acid and Glycine, and then someone will go, “Well, I’ve got Chromium Nicotinate and the Tri Amino Spectrum patented and trademarked under the thing,” you know.
Jeff: So, for people out there with Diabetes and/or for body builders, and not for everyone in between that wants to make their Insulin more effective should they just take Brewer’s Yeast?
Matt: They should, as well, use Brewer’s Yeast. Brewer’s Yeast is cool, and we use Brewer’s Yeast in a lot of our products. We’ve got some more products coming out in the future with really
cool versions of Brewer’s Yeast.
Jeff: Better patent it.
Matt: No, well you can’t, and this is the whole thing, these are Natural. But, the cool thing is Yeast is like a sponge, so you can feed Yeast things and it sucks it in and converts into the form our body wants.
Jeff: The active forms, right.
Matt: So, we can tailor make and custom make Yeasts, which we are working on right now for our future products. We already use Yeasts to supply Selenium and that sort of stuff, so it’s pretty cool, but at the moment, basically, they are Brewer’s Yeast. All we’re doing is screwing around with the ratios a little bit so that way we can stack them on top of each other and make sure we get the right ratios of Nutrients and that without overdosing on certain things like Chromium which you could do easily just by consuming Brewer’s Yeast. I don’t think beer works, I did it for years, I drank beer.
Matt: No beer, not beards, you’re weird. You can suck the Brewer’s Yeast out of someone’s beard if you want.
Jeff: There’s a beer in there.
Matt: What? You Kiwis, I can’t understand what you’re saying.
Jeff: And, a cheer as well.
Matt: Anyway, so then when you look at it the funny thing is, most people when they talk about making a Supplement to help Blood Sugar control it’s Chromium with B Vitamins, and that’s why, because they’re trying to recreate Glucose Tolerance Factor.
Matt: Mm. Which is a very important component. So, Lipoic Acid is cool, and the point is with Lipoic Acid the studies show that about a 200-milligram dose for Blood Sugar control is about as good as you’re going to get. A lot of people are going 600 milligrams just to get a competitive edge, but you’re better off having 2 or 300 milligrams three times a day with your meals and it will help to drop Blood Sugar for a period of time. Once you build up your Lipoic Acid levels it doesn’t do much anymore.
Jeff: So, Matt, if you’ve got more we’ll keep going, but just remind me, I want you to summarise this whole thing for me, go through everything from GLUT4 to Insulin to whatever.
Matt: I hope you’ve been taking notes.
Jeff: No. But, what I want to do is look at this from a point of view of disease control and what people should be doing, like a summary, but also then for people who have a problem and want to lose some Body Fat as well too, and that’s healthy, but also then from a Muscle Building point of view, how people can utilise this information to be able to achieve the results they’re looking for.
Matt: Yeah, well we’ll write up our plog…
Jeff: Your plog?
Matt: What is it? A podcast blog or something?
Matt: Anyway, we’ll write up something like that with those summaries that people can download and read. But, what we’ve said so far is if you’re Type 1 Diabetic it’s a management issue, we want to stop those spikes in the Blood Sugar causing you to go blind and that sort of stuff.
Jeff: And, you use that with your medication, with your Insulin?
Jeff: What else?
Matt: So, it’s Bilberry, Hawthorn, and again, a lot of Antioxidants and Lipoic Acids and that stuff. Again, Glucose Tolerance Factor is important for your Insulin to be able to work especially when you’re using Insulin injections, and watching for Ketoacidosis, preventing that complication.
Type 2 Diabetes; 85% of people diagnosed with Diabetes are diagnosed with Type 2, that’s an Insulin Resistant Syndrome. When you’ve been diagnosed Type 2 Diabetes if we can preserve your Pancreas and make sure we don’t totally screw your Pancreas while you’re going through this then we can actually reverse it a lot of the time.
Jeff: What’s the best way to do that, Matt?
Matt: Working with people for Diet, Exercise and Macros.
Jeff: Yeah, I was going to say weights has got to play a big role, and Resistance Exercise.
Matt: Oh hell yeah, and strategies, and then measure your Blood Sugar in response to different Diet and Exercise strategies. Using things like Biotin, Gymnema, Berberine is a cool one, but then looking for the causes that are specific for you, which is Inflammation, Stress, Cortisol, Estrogen Dominance, Thyroid Dysfunction and any other Genetic conditions. If you’ve got a family history of it, you are definitely predisposed to it for various reasons.
Jeff: Obviously, things like Sugars play a big part, Alcohol plays a big part as well, so those things should be avoided.
Matt: Yeah. And, looking after the Liver, loading up on Glucose Tolerance Factor. An interesting one, we talk about Triglycerides in the Bloodstream, so if you’ve got too much Fat floating through your Bloodstream it causes Insulin Resistance. What makes that worse is the type of Fat, so you know how people talk about Omega 6 to Omega 3 ratios, our Omega 6 to Omega 3 should be around two to one, maybe out to about four to one, that’s about our ideal, apparently, it keeps you a lean mean fighting machine. If your Omega 6 levels start to increase—and, we can do that in an animal by putting them on a grain feedlot, and the same thing can happen to us when we put ourselves onto a grain feedlot, stack that with eating animals that are also on a grain feedlot and the next thing you know your Omega 6 to Omega 3 ratios can go from to two to one out to six to one, out to 12 to one, 32 to one is a common thing for Australia; westernised countries are common around 24 to 32 to one. The Middle East, apparently, has gone out to about 60-something to one because of their abundance of grains and all the grain fed animals as well. So, when you look through those stats of the populations that have got high levels of Diabetes, yeah we’ve got all the Obesity in the westernised countries, but you’ll find a lot of the Middle East areas have got massive amounts of Diabetes because they’ve got crazy ratios of Omega 6 to Omega 3.
Jeff: Qatar and all that, and Kuwait.
Matt: Yeah. And, the rest is the Indigenous group. The Indigenous groups that have been isolated, and isolated groups that were forced to eat local, such as Islanders, Australian Aborigines and all those sorts of people, they didn’t have a massive variety of different things, so they ate what was local, and what was local was often processed local as well. So, it was basically high fibre, so low GI Carbohydrates and high Protein Diet with a lot of good Omega 3 Oils because everything was grass fed or fish from the ocean or grazing animals, so high Protein with high Omega 3 levels. As those Indigenous cultures get exposed to a more westernised Diet with processed foods, simple Sugars, Alcohol and all those other bits and pieces, they have not had enough generations to get used to processed foods.
I think the Agricultural Revolution was 150,000 years ago but that didn’t happen in Indigenous communities. The Industrial Revolution was probably 150 years ago where they started processing and refining everything or whatever—I don’t know these dates exactly, but the Agricultural Revolution had so many generations through other cultures to get used to eating Cereals and Grains, then suddenly 150 years ago we started taking all of the fibres and processing them and making these fine white powders to base our Diets on, and that didn’t happen in any of the Indigenous communities. It’s only been in the last one to two generations, maybe three generations that they’ve had access to processed, refined Cereals and Grains, highly refined sweeteners, and different ratios of Omega 6 to Omega 3, and suddenly they’re not adapting. Have a look at the Australian Indigenous Aborigines, they had to work very hard to get food that was basically sticks and twigs, high Protein and a very high percentage of oil, and they did that for, who knows, up to 50,000 years, and they had that length of time to get used to that. But, 200 years is how long Australia has been colonised, so we’re only looking at these guys 100 or maybe 150 years, half a dozen generations at the most to adapt. So, in the big scheme of things they’ve only had a blink of an eye for evolution to help their body to adapt to a western Diet that the rest of us have had a lot longer. So, that’s the problem with these communities, they’re just not designed for it.
Jeff: So, good sources of Omega 3? We know Fish, obviously.
Matt: Well, Grass and Plankton.
Jeff: Grass and Plankton?
Matt: Yeah. So, if you don’t want to eat Grass and Plankton find an animal that does want to eat it and eat that, because that’s pretty much the food chain where it’s going to be coming from.
Jeff: Are there any good ratios of Omega 3s from Nuts or Seeds, Matt?
Matt: Yeah, but they’ve got a big variety. We use Pomegranate Seeds, they’re really good for special forms of Omega 3s, as are Safflower Oils and that sort of stuff.
Jeff: They’re pretty hard to eat though, not too many people are going to chew those up.
Matt: Yeah. Linseeds.
Jeff: That’s about it?
Jeff: And, lastly Matt, for the body builders? What can they take from this and learn from this for improving Muscle size? And, Fat Loss as well, too?
Matt: All those things. Basically, everything we’ve said that will improve Insulin Sensitivity to stop someone from getting Fat and getting Diabetes will help anyone build Muscle, because the more sensitive you are to Insulin the more sensitive you are to the Insulin-Like Growth Factors.
Jeff: And, timing obviously, is important?
Jeff: Specific Anabolic phases should be happening directly after training?
Matt: Yeah, yeah. But, everyone is still a little bit different, so a lot of it’s just working with your coach, you do strategies and you work on them, but typically yes. But, it just depends; if you want to build Muscle it’s all about utilising opportunities to replenish that Glycogen and stimulate Insulin and Insulin-Like Growth Factors around training. If you want to Burn Fat it’s about keeping that Glycogen moderately depleted to keep you sensitive to Insulin until you can replenish that Glycogen.
Jeff: Yeah, looking after the Liver sounds—it’s funny, it’s brought the Liver into a whole new light for me, what you’re saying about the receptors and the importance of—no information.
Matt: It’s freaky. It does the same for Cholesterols and all that sort of stuff.
Jeff: Right, cool.
Matt: If you fit into a category of Polycystic Ovarian Syndrome then you’re on your way to Type 2 Diabetes, so you need to implement all the changes as if you’ve got Type 2 Diabetes to make sure you don’t get it, because the only difference between Polycystic Ovarian Syndrome and Type 2 Diabetes is your Sugar doesn’t go too crazy yet. Everything else the same; Metabolic Syndrome is exactly the same, and Insulin Resistance Syndrome, all of those sorts of things the doctors can diagnose you with, and they are pre-Diabetes things. If you’ve had Gestational Diabetes, which is during pregnancy where the Blood Sugar spikes, same deal.
Jeff: Last word on Diabetes, Matt, and then we’re going to get into some FAQs?
Matt: I can’t remember, but I think the word Diabetes Insipidus actually comes from sweet tasting urine. I wonder who the hell come up with that?
Jeff: I don’t know, it wasn’t me.
Matt: Imagine that, going, “Mm. Oh, you taste like Diabetes.”
Jeff: Yeah, it’s funny, isn’t it?
Matt: So no, no last word.
Jeff: Could you give me a test later?
Jeff: Matt, okay so getting into the FAQs.
Jeff: This one is from Nathan: “Hi guys. I’m currently 9 weeks out from my next show, but two weeks ago I got an Inguinal Hernia.”
Jeff: “I needed an operation that day because it might have got entangled. It hit me from left field as I was completely gutted, I was well on track with dieting and training.
Matt: Ha! Gutted.
Jeff: No pun intended. “Plus, my body was better than ever. Now, it’s been two weeks, recovery has been good and I’m starting to be 100% active, but due to my opening my own business and trying to look after myself so I can still compete, Stress, Fluid, Swelling, Weight, Muscle Breakdown, I’m going through is upsetting. I need advice on what to take to speed up recovery, help maintain Muscle, release Fluid, relieve Stress, reduce Swelling, and get me back in shape as soon as possible so I can compete. But, most of all, have a healthy recovery. Any help would be much appreciated, Nathan.”
Jeff: Poor bastard.
Matt: I’ll tell you a funny story about Inguinal Hernias.
Jeff: Inguinal Hernia, what is it quickly, Matt?
Matt: It’s when a bit of your Bowel pops out into your Groin, usually when you’re doing the leg press too much or something like that.
Matt: I was in the garden with the wife the other week and we’re doing all this heavy lifting, and what I did was I went and got one of my nuts and I popped it up over the top of my shorts and I went, “Oh, I’ve got a Hernia, I’ve got a Hernia,” and my wife went, “Oh, no look at that,” “It’s just my testicle.”
Jeff: How did you get the bean above the frank?
Matt: I got it above my shorts, I’m a lefty.
Jeff: Oh my gosh. A lefty, okay. The legendary left long nut.
Matt: Yeah, he’s a star, lefty is a star.
Jeff: That’s enough about that. Well, Toni will probably cut that anyway.
Matt: Anyway, so what I would use is CORT RX and AMP V. What? Toni will cut lefty?
Jeff: Oh. Maybe not.
Matt: The wife tried to flick it.
Jeff: Then she worked out what it was.
Matt: Yeah. So, with CORT RX basically you need the Anti-inflammatories and the Stress control, so get straight on the CORT RX, but I’d do one capsule three times daily just to give a steady blood level of it at a low does. I would definitely hook into AMP because AMP is a very good Anti-inflammatory, AMP is very good for the Bowels, a very good Muscle relaxant in through the Bowels as well, and it definitely helps with that Fat Burning and strip out a lot of that sort of stuff and preserve a lot of that Muscle. But yeah, hook into those two things for starters, that’s the first place I’d start.
What’s quite freaky is you can use PROTOTYPE A to improve healing and recovery, it does some crazy things for the Muscles of the Abs, it makes it look like a brick wall, it really thickens up the Muscle layer in the Abs.
Jeff: Cool. So, we’ll send out an AMP and CORT RX and PROTOTYPE 8 to help Nathan get back on it. It’s one of those things too, Nathan, you can’t speed up things beyond what they’re naturally going to take. I mean, obviously, you can take these additional formulas which will help with the healing but it’s a process and you just have to, effectively, resign yourself that it’s going to take some time. If you continue to worry about it that Stress is going to cause Inflammation.
Matt: Hydrolysed Collagen would be a good idea too, because you need to toughen up that Connective Tissue and bring those Connective Tissue fibres back closer together to help fill in the holes.
Jeff: And, I should rephrase what I said, you can speed up recovery but you have to go through it, so whether it’s going to be four weeks or eight weeks or whatever it’s going to take…
Matt: Oh, yeah you can’t push it.
Jeff: You have to allow yourself to heal. But yeah, Nathan, best of luck and we’ll send out that AMP, CORT RX and PROTOTYPE 8 to help, so hopefully that helps you.[0:42:49] Okay, this one is from Natalie: “Hi guys, I don’t need to say how amazing your podcast is but I want to say that it’s changed my life and I’m really hoping you can help me with the following: Spider Veins on my calves are now spreading to my thighs. Horrible Cellulite on my upper thighs and Glutes, it’s cold to touch even after an intense workout. Three; very painful Periods to the point I take one to two days off every month. Four; it seems almost impossible to lose Fat from my thighs and keep it off. Are they all linked?”
Jeff: “I have hit my thigh Fat Loss goals in the past but find I struggle to maintain lean legs for more than about three months. It’s a never-ending cycle that I’ve struggled with for the past five years. All my friends know me as the Training Freak, and Healthy Eating Freak, but unfortunately my body doesn’t look like I put in any effort. I’ve always slept terribly even as a kid, but I still make it to the gym each morning. I eat well and train hard with a variety of weights and Cardio. I dry brush every night before my shower, massage my legs with coconut oil and bio oil, foam roll my legs most days, and I don’t take the pill or any other contraceptive. I’ve tried ALPHA VENUS, T432, and SUBCUT. The VENUS has helped but I didn’t have too much luck with the SUBCUT. Could you please tell me what else I could do, or supplement, to shift the Cellulite, lose the Fat from my thighs, and stop the spreading of those Spider Veins. Would Collagen supplements help? Also, Rach White is my new coach and I’m two weeks into my program and I’m excited to see how my new eating and training regime will help with my Fat Loss goals. Thank you, legend. I really appreciate it, Natalie, from Manly, New South Wales.”
Jeff: Mattie, I’m glad she’s training with Rach, we’ll give her a special shout out because she’s just won the World WBFF title. Unbelievable. She looks absolutely amazing.
Matt: Mm. The best in the world.
Jeff: We did a video which we’re actually putting up onto our page, so maybe have a look at that, but anyway, Rach is definitely going to help you.
Matt, what’s going on here? These ones really upset me because it sounds like they’re putting in the effort and I believe [overtalk] [00:45:04].
Matt: Yeah, it’s the worst, eh.
Jeff: And, not getting any results.
Matt: But, it’s also the best type too, because they’re doing the hard bit. When someone says all those things and then they go and say, “But, I’m not prepared to change my Diet or do any exercise,” then it’s like, “Oh well, you’re stuffed.”
Matt: So, you’re doing the hard work and you deserve results. I would measure the MTHFR Gene, and Homocysteine and make sure there’s not a Genetic Polymorphism where your body is struggling to get the Co-factors it needs for the things like ALPHA VENUS and that to work.
Jeff: If you were a betting man, Matt, you’d say that’s…
Matt: This is Estrogen Dominance. Estrogen makes the painful Periods, it makes the Sticky Blood, it makes the Veins, it [overtalk] [0:45:40] things, it holds the Cellulite, it holds the Fat, it screws up with your Sleep, it makes you think too much, everything here is Estrogen Dominance. But, we need to convert the Toxic Estrogen that holds Cellulite and makes the Blood Sticky into the weak Estrogen that protects you against all those things. The VENUS helps to do that, but it needs other Cofactors to achieve that, such as Folate, B12, and that sort of thing, so Methylation Cofactors. Usually, though, there’s enough of them in the VENUS itself along with the other stuff you’re getting from your Diet to achieve this, and obviously, it’s not, which makes me think there may be a Genetic block or a problem where the body can’t convert the stuff you’re supplementing with into the stuff that your body uses.
Fortunately, in Australia we’re not allowed to add the stuff in that your body uses directly, except we’ve worked out a way. When our new Multi comes out that will make all the difference, because our Multi has all the activated forms of Folates and B12 and everything in it, so they’re going to bypass any Genetic problems and go straight into the form that your body can use to combine with the Glycosylates from the Broccoli, with the Folates, the B12s, the other Methylation Cofactors, and that will totally deactivate the Estrogen so it can go into the Bowel and be removed.
The causes for this, at the moment, apart from Genetic issues, could be Gut problems. If you’ve got a major overgrowth of too many bad bugs in the Gut they can be re-liberating that Estrogen and putting it back in, which can recycle it. So, measure the MTHFR Gene, measure Homocysteine, you could get Folate and that measured but it’s usually irrelevant, so basically just measure those couple of things. When out Multi comes out hook into that, and in the meantime, try to purchase something online, the activated form of Folic Acid 5-MTHF, so 5-Methyalinetetrahydrafolate at 1000 micrograms, and then get a Methyl B12 as well, which will be written as Methylcobalamin, take 1000 micrograms of that as well. Keep taking the ALPHA VENUS, but you need BLOCK E3.
Jeff: I was going to say BLOCK E.
Matt: Because BLOCK E3 is more important than the SUBCUT for you. You can still use the SUBCUT, but I would even have a break from the SUBCUT if you’ve been using it for a while and just really butter up on BLOCK E3.
Jeff: Two or three times a day, Matt?
Matt: Yeah. The problem is, SUBCUT is very good at powerfully liberating the Fat but the Estrogen won’t let that happen.
Jeff: No, that’s right.
Matt: So, if we just get the BLOCK E3 in for a period of time first and then try the SUBCUT again and you’ll notice a big change.
Jeff: It’s like safe cracking, Matt. I look at these chemical straight jackets that some people have, and this is the frustration where people say, “Use this, it works great,” and then the friend takes it and they go, “I used it but it did nothing for me,” and that’s because your Hormonal Profile, the way that your body has prioritised things, the underlying MTHFR, issues in your own body, we are individuals, we’ve got our own thing.
Matt: And, with everything, you learn more from failure than success. So, as we’ve seen here, through a process of elimination we know what hasn’t worked and that can give us an indication of what’s going on.
Jeff: Cool. Natalie, best of luck to you. Try those things.
Matt: We’ve got some of that Multi made up as part of the trial.
Jeff: Should we send some out to her?
Matt: Send some out to her anyway.
Jeff: Alright. I’ll get Elsa to send some out.
Matt: She might be one of the first people to try it. Make sure she signs a waiver in case something happens.
Jeff: Alright, cool. Okay Natalie, best of luck and let us know how you go. We’ll send you out ALPHA VENUS, BLOCK E, and maybe the MULTI, and if not, take the advice Matt said, and jump on some of that. We’ll have to get sign off from some legal people I’m sure.[00:49:14]
Okay. So, this one is from Sherrie: “Hi, I love the CORT RX, it’s my go to supplement as high Cortisol levels an Stress remain my top three priorities since I started using following a training method two years ago, which is how I found ATP Science products. To me, there is a noticeable dramatic change and a [0:49:37] feeling when I’m on it versus those three to four week break cycle periods when I’m off it, and allow the product to remain effective.
However, I’ve recently become pregnant for the first time and notice your products have a “Do Not Use while Pregnant” disclaimer. I cried, (cried uncontrollably). Is there a combination of Natural ingredients that are pregnancy safe that could provide similar results as your CORT RX? Is CORT RX actually pregnancy safe, and the labelling is more a legal precautionary requirement? I really don’t want to go nine months without the CORT RX. PS, if you could confirm if any of your other products are pregnancy safe too. Thanks very much.”
Okay. Before you say anything.
Matt: You start it.
Jeff: Look, I don’t know the question as to whether these Herbs are safe to use during pregnancy, but there is no way on God’s green earth that we can ever say, “Sherrie, you can use them,” from a legal standpoint. Matt, over to you.
Matt: Well, we’ve just had three babies between us, with our wives involved, we’ve had three babies in three years…
Jeff: You’ll make a wonderful mother.
Matt: Yeah. Well ours were never allowed to take any of these products during pregnancy or breast feeding. So, we wouldn’t even do it with our own families, so don’t you do it.
Matt: But, have a look what’s in it. The main ingredient in the CORT RX that’s helping with the Stress and Anxiety is Turmeric, and Turmeric is fine for you to consume during pregnancy. The Withania is a very powerful extract, Schisandra is also a very powerful extract, Rhodiola is a very powerful extract.
Jeff: You can find these things, Matt?
Matt: They haven’t been studied with pregnancy, but Turmeric has got thousands of years of use with pregnancy. And, what you’re looking at is the therapeutic doses of Turmeric for the Stress and Nerves is only a gram, so start hooking into Turmeric as part of your Diet throughout the pregnancy.
Jeff: And, the simple ways you could do it, I mean Toni buys the Curcumin powder, curry powder, a lot of Indian curries have it. One of the things I love doing is fresh juices, so using Turmeric and we use a lot of Ginger which can be really good, officially, if you’re susceptible to getting a bit of that sort of stuff, and throw in a bit of Celery or Apple with it as well.
Matt: Yeah, all those things are fine, so throw all those sorts of things in. Other things you can use during pregnancy to help with Cortisol levels and that sort of stuff, the one I recommend you look for and supplement with is Magnesium. Magnesium is very safe and effective and is recommended for use during pregnancy, and can control Cortisol, and has as an Adaptogenic function as well. So, those sorts of things are all fine, but basically go for foods, and try to incorporate them all into your Diet.
Jeff: And, throw in a bit of Folate. Toni when she was pregnant used to use a bit of Kale and she’d put that in, and you can use baby Spinach leaves and that sort of stuff as well in your juicer, or just eat them in your Diet because you need the Folate too.
Matt: Yeah, all those sorts of things, and you’ll probably be taking a Folate through the pregnancy anyway, and the Folate is really important for regulating Neurotransmitters, but it needs B12 with it to work, so just double check the dose of B12.
Jeff: And, if you can get Folate as opposed to Folic Acid, is that right?
Matt: Yeah, you want Natural Folates if you can, but I don’t know if you’ll get them in Australia, but other parts of the world I still don’t think they do the 5-MTHF which is the actual one that works during pregnancy.
Jeff: So, best of luck with that Sherrie and we’ll look to see little baby Jeff Matt.
Matt: Is that what she’s going to call it? That would be cool. Jatt.
Jeff: Jatt or Meff.
Matt: Don’t call it Meff. All meffed up.
Jeff: No. And, if it’s a girl it’s character building to be called Jeff.
Matt: Yeah, it would be. How did you deal with it as a little girl?
Jeff: I used to cry myself to sleep every night.[00:53:31]
Okay, this one is from Jess: “Hi guys, I have a couple of questions. I just finished listening to the Secret Women’s Business podcast and I picked up a few things for me. I was on the Pill a few years ago and was getting headaches all the time so my doctor switched me to Implanon which is the implant in the arm, and the headaches never stopped, especially around that time of the month, plus I gained nearly 10 kilos. I’ve always had tender breasts and would randomly cramp up for days at a time if I was at that time of month, and then at least a week before and a few days after. After listening to your first podcast about this I started ALPHA VENUS and have noticed heaps of changes; headaches are less, pains are less and moods are better. However, my other issue is, I get my periods every two weeks, sometimes I’m lucky and it won’t happen but 90% of the time it does. What do you guys think that could be?
I know one side effect of the Implanon was irregular periods but I didn’t think that it would be like this. On my last year of it, thank God, but I’m not game enough to go back on the Pill, which I was originally prescribed, to help with the severe pain I got with my period. Before going on the Pill, I was in so much pain I couldn’t move and was nearly taken to hospital on many occasions. Is there anything you guys can suggest? Love the podcasts, they have helped so much and I’m learning something new every day. From Jess.”
Jeff: Well, that’s pretty full on, Matt.
Matt: It’s an easy one. When you’ve got a relative Estrogen Dominance what happens is your Blood goes Sticky, that causes Migraine Headaches and that causes painful Periods. The Estrogen component that does that also makes the Period, so it makes Blood. Progesterone is supposed to hold the Blood in. So, we know you’ve got too much Estrogen because the Implanon and the way those pills work is they convert a weak Estrogen to a strong Estrogen, so you’ve probably got normal levels but very strong Estrogen activity. If you combine that with a tendency to have lower levels of Progesterone then you’re making Periods and you can’t hold it in and you’ll have a Period every two weeks, as well as the signs of Estrogen Dominance.
So, often when we see signs of Estrogen Dominance we’re trying to work out, “Do you have too much Estrogen or not enough Progesterone?” In this case, you’ve got a bit of each. You’ve got too much Estrogen from contraceptives and you’ve got not enough Progesterone because that just seems to be the way you are, and it was probably the original problem. Because, if you started off with not enough Progesterone then you would get all the painful Periods and stuff anyway, and then they go and put you on an Estrogen related Pill that made it worse. Whereas, if you’d focused on increasing Progesterone production enhancing Ovulation and making a good Progesterone surge after that to hold the Period in and offset the Estrogen Dominance that may have corrected a lot of those per-menstrual dramas in the first place.
So, you’re on the right track, the VENUS is the right product to use. The way to use it though is to take four every morning with breakfast. If you do that what you’re doing is you’re starting to work on a consistent level with the Pituitary Gland where it will tell your body, on a daily basis, to induce Progesterone surging and that will hold your Period in. The other thing you might need to do is very similar to the last one, you need Folic Acid and B12 to help with the VENUS to detoxify the Estrogen that’s caused by the contraceptives. So, when our MULTI comes out that will be perfect for you. In the meantime, and I don’t know how you’re doing VENUS at the moment, but just throw four in in the morning and it will work, it will help to build up that Progesterone.
Jeff: Alright, well we’ll flick out Jess a ALPHA VENUS. And, with the Implanon, I think one of our other girls over in WA, I’ve forgotten her name, she had it taken out. I’m not suggesting that you do, by the way, but I appreciate these are things that you might want to consider. But, again, talk to you doctor about any of that sort of stuff, and in the meantime, Matt, she should still be using the VENUS anyway, right, even with the implant?
Matt: Oh hell, yeah. Smack it in. Bloody oath.
Jeff: And, when she comes off, Matt, is there any other advice?
Matt: It will just be the VENUS and the MULTI, and when the MULTI comes out you’ll need that to make the VENUS work better.
This one is from Michelle: “Hi guys. Have a question for you. I’m still trying to lean out my legs,” we spoke to Michelle a while ago “I think they’ve actually become even more Muscular despite a tube of each of the SUBCUT and BLOCK E3. I did a bottle of AMP V and Fasted Cardio and didn’t notice any difference in my physique even with some hip Cardio multiple times a week. I’m at my wits end here. I take two caps, total of four ALPHA VENUS morning and night, and I’m due for my three months break soon, but I’m a bit concerned that I’ll put on weight without these daily regulators, not sure what to do during that break time.
I’m thinking of trying a combination of AMP V, ALPHA VENUS and T432 for next month. My basic history again: I’m a 48-year-old, non-menstruating female with a history of PCOS diagnosed 15 years ago when trying to have kids. Hashimoto’s Thyroiditis which I manage with Amour and Cytomel. Though I have to monitor it closely in order to keep my levels optimum my T3 levels are constantly high and my free T4 is low, and my overall TSH is within range. Multiple Sclerosis which I managed through Exercise and Diet, my Grain Free Diet is very clean and low dose Naltrexone. Do you think this new combo would be beneficial? All three products has a hefty price tag but the issue is beginning to affect my self-esteem and mood. I know there is no silver bullet and am more than willing to put in the work but I think my body needs some endogenous support. Thank you, Matt and Jeff for your amazing work and content. My two cents worth—when you guys ask, “How are you?” I do want to hear how you are. It’s nice to hear what’s going on in their lives if ever so briefly. It’s not all about the content, if they’ve been travelling or pulling all-nighter’s in the lab might explain their lovable loopiness.”
That’s nice of you to say.
Matt, I do remember talking to Michelle, I thought, “Muscly legs, that’s something I would like to have especially in the calf region, for myself.” But, this is obviously frustrating, and again, another one where there are some individual issues going on here and maybe some interaction with some of the medication as well might be causing some issues, but I don’t know, Matt. Over to you, what do you think?
Matt: Don’t know.
Jeff: Well, you’re stuffed then.
Matt: Thanks for your question. No, it’s a weird one, but what we’re looking at, and it’s a bizarre thing. What you’re wanting to do is change some Genetic structure. Everyone has particular strengths and weaknesses, and what you look at as a weakness other people look at as a strength, and it’s pretty hard to fight against the body, when the harder you work the body just wants to hold and put Muscle onto your legs.
Jeff: I remember Robert de Castella, the long-distance runner, but he had reasonably sized legs, big calves and that as well. Put them up against the Ethiopians and they were like a rake. So, you can increase high intensity Cardio and things like that…
Matt: Yeah, well that’s what I was going to say, the only way to totally change something that’s been occurring over a long period of time is to make a total change. So, if you’ve been eating a certain way, providing a certain amount of Carbohydrates and doing a certain type of Exercise you’re going to have to just turn everything on it’s head. So, what I would do is try to focus on improving Mitochondrial Density of a Muscle rather than Muscle mass, so researching things that improve Mitochondrial Density and Mitochondrial Biogenesis because that makes leaner wirier Muscles and less roundness to the Muscles, and it makes them longer and stringier. To do that that’s high intensity Cardio as opposed to slow and steady. Remember Anne -Marie Lassarie?
Jeff: You took the words out of my mouth.
Matt: Anne-Marie was saying she doesn’t like doing high intensity because it actually changes her Muscle valleys from being big and round to long and stringy.
Jeff: Yeah, that’s right.
Matt: The other thing is, like changing your Diet up, if you go to a full Keto Diet, if you take away a lot of the Carbohydrates and focus on a higher Fat but Protein adequate Diet, so just the right amount of Protein so you’re not losing too much, and then focus on your Calories coming from Fats as opposed to Carbohydrates. That forces the body to change and make more Mitochondria per Cell, which will change the structure of your Muscle body over time. But, like I said, you’re fighting against something that other people want, but this is the way your body adapts to your Diet and Exercise.
Jeff: If you’re using PROTOTYPE 8 don’t use it on your legs, and this is for anyone really, but being a serm it’s going to be fantastic for females to build Muscles, so if you are using it get off it.
Matt: Regarding the other stuff you mentioned, for the Thyroid I would definitely go and get your Reverse T3 levels measured to see if your T4 is converting down to Reverse T3 as well as the T3 Pathway, because that Inflammation that’s associated with Autoimmunity and PCOS can contribute to that. So, I would definitely do it.
Jeff: So, Matt, what supplements of ours do you recommend that she use or continue to use, and we’ll send those out for Michelle?
Matt: Well, keep using the T432. I would continue to use the AMP V for sure, so then definitely the AMP V, the ALPHA VENUS and T432. She’s on the right supplements, it’s just a matter of totally shaking the training up, that’s the biggest thing, your body is adapting to these things including Diet and Exercise. So, you’ve made changes to your other supplementation now we’ve got to make wholesale changes to your Diet and Exercise strategies to freak the body out and adapt.
Jeff: Okay, cool. Otherwise get into Ultra Marathon—no, I’m just kidding.
Matt: Yeah, contact Robert de Costello and start jogging. Go to Kenya and get some water.
Jeff: Michelle, again let us know how you get on. Hopefully we can find a solution that you’re happy with and that works.[01:03:50]
This one is from Alex: “Hi Matt and Jeff, I just want to say that I absolutely love your podcast and have been listening to you non-stop since I found it. I really desperately need your help. I am a female 26 years old and the following symptoms all started about four years ago after I was really sick with a really bad stomach bug.
I suffer from the following problems: severe Bloat daily, poor Concentration and Memory Brain Fog, Abdominal Pain after meals and every morning for the first hour after waking, Constipation 95% of the time, Tiredness; I feel sluggish and fatigued all of the time, Headaches, Dizziness, Blurred Vision, Nausea, Restlessness. At nights, I find it hard to get to sleep, Muscle soreness and weakness, Weight gain which I can’t lose, weight on my arms stomach and thighs. I definitely know that I have Candida and it is growing on my tongue. I also believe I have Leaky Gut, Adrenal Fatigue, Low Functioning Thyroid and High Estrogen.
Can you please advise what Diet I should be following and what Supplements I should be including as well? There is so much conflicting information out there, I just want to know if I’m on the right path. I’m currently following a high Protein, Low Carbohydrate, no Sugar, Diet which seems to be helping and using the following supplements.” Which, Matt, you can see, and again are a lot of the ones that you made for another company.
Matt: Some of them.
Jeff: “Thanks so much for your help, keep up your good work, kind regards, Alex.”
Matt: Cool. This is a classic. When you get the green apple splatters and these Gut bugs and that sort of stuff, what it’s often doing is it’s purging out a lot of your Gut Flora. Your Immune System is firing up, it can’t afford to tell what’s caused it, so it just kills and poisons everything and flushes the whole lot out. As you’ve noticed the Candida, which is a yeast fungi organism, it can migrate to certain areas and can hide, and it actually roots into the Gut wall and it makes it very hard to shed as it becomes a larger organism. So, it goes from a single cell spore through to a whole mushroom looking creature that’s got roots and everything that grabs all the way through the Mucosa.
Jeff: A great word picture there.
Matt: Yeah, wait till you see the pictures of it in the Anti-Candida document. We’ll put up my Anti-Candida document that talks about foods and all that sort of stuff, someone will it out.
Jeff: Elsa will have it for sure.
Matt: Yeah. But, what happens then is you wipe out all their competition and they thrive, they grow, they feed on the same foods. That treatment that you’re currently on it’s not targeting fungi and Candida, it’s actually targeting Bacteria. So, what’s happened is, you’ve wiped out your Bacteria, your colonies of fungi and that have probably overgrown, but your treatment is constantly killing off more Bacteria. The fact that you’re going on a Low Carb Diet, yeah that will be starving the Candida to a certain degree, but it’s definitely starving your good friendly Bacteria as well.
There is a thing that we call Competitive Exclusion. It’s like when you’ve got the Gut bug you went and threw Roundup poison all over your yard and killed off all your grass. The weeds that were resistant to it have grown, now the weeds have filled up your lawn and there’s nowhere for your grass to grow back, and the problem is, you’re still using the Roundup, and then the weeds are thriving and growing. So, you’ve got to get rid of the [Antimicrobial stuff that you’re taking and move onto an Antifungal sort of protocol.] REFER TO LATER PARAGRAPH BELOW
Jeff: That’s the [1:07:14].
Matt: Yeah, so one of those products there will be full of a variety of Herbs that are designed to kill Parasites…
Jeff: Like Wormwood?
Matt: Yeah. That form there is actually more effective at killing Bacteria than it is at Parasites and Fungi and that sort of stuff. [So, the big point is, you need to go and do more powerful Anitfungals and leave the Bacteria alone.] THIS IS IN CONTRADICTION WITH THE ABOVE STATEMENT, I THINK IT SHOULD BE SHE NEEDS TO GO AND DO MORE POWERFUL ANTIFUNGALS NOT ANTIMICROBIALS.
Jeff: What are the best Antifungals, Matt?
Matt: There’s a Herb I love from a place I don’t like as much—no, there’s a Herb called Horopito from New Zealand. No, we’ve just been going the Rugby thing, it’s really upset me, so don’t look at me anymore with your black and white shirt you’re wearing.
Jeff: By the way, for our international—well, England would have heard about it by now, but New Zealand is the most highest percentage winning team in the world, 75% win loss ratio, which is better than Real Madrid, better than New York Yankies, better than any of them combined. Now there’s only one sport I really, really care about and that’s obviously Rugby New Zealand.
Matt: There’s only one time that Jeff talks about being a Kiwi and that’s when the All Blacks are bloody playing.
Jeff: That’s exactly right. Well, I’m very proud of that.
Matt: Yeah, you should be.
Jeff: We thumped the Wallabies, which is the Australian team…
Matt: Yeah, alright anyway.
Jeff: Let me put it in context. I have to bring clarity, Matt.
Matt: Back to Alex’s stuff here, we don’t need to hear your issues and weirdness stuff. But, anyhoo, there’s a Herb called Horopito from that place there, and it’s a very powerful Antimicrobial. One of my favourites, which is a much, much better one…
Jeff: Is it Australian?
Matt: Actually, it is.
Jeff: That’s the only one it’s good at is killing fungus.
Matt: Well, you put the fun in fungi, you mouldy…
Anyway, it’s a stupid game anyway. So, Dorrigo Pepper, it’s an Australian mountain pepper. They both contain and active ingredient called Polygodial, which is a very effective Antifungal. The components of Coconut Oil are very powerful Antifungals, there are quite a few of them out there. Vietnamese Mint is another very powerful one, again contains Polygodial. Load up on those Antimicrobials and stop attacking the Bacteria, give them a chance to grow back. HERE AGAIN I THINK THIS SHOULD BE LOAD UP ON THOSE ANTIFUNGALS. There is a thing called Herxheimer Reaction, which is a reaction you get when you kill Bacteria, it’s Constipation, Nausea, Diarrhoea, Bloating, Farting, Fluid Retention, so a lot of the symptoms you’ve got can actually come from killing Bacteria. So, what I would do is start putting in some other Yeasts as well that compete with Candida, so Saccharomyces Boulardii, Saccharomyces Cerevisiae, throw those things in, throw in your Dorrigo Pepper, your Horopitos, those sorts of things. Follow our Anti-Candida protocol, start killing off a lot of these fungi and moulds, and then start throwing in some good friendly Bacteria that might start coating your Gut and start Digesting your food, because it’s the Bacteria that feed on your fibre that make the Short Chain Fatty Acids that rebuild the Gut wall, it’s the Bacteria feeding on your fibre that colonises your Gut wall and work Competitive Exclusion to starve off and push out the Candida. You never get rid of Candida, all you’ve got to do is take a big chunk off the population so your normal Gut Flora can keep it in control so it’s not migrating to your Tongue and your Skin and your Ears and your Vagina and that sort of stuff, Jeff.
Jeff: Are you saying my Vagina?
Jeff: It’s good to know.
Matt: I don’t know, really. I don’t know what state it’s in yeast wise. But—how’s that going to go down?
Jeff: This is getting weird.
Matt: So, Anti-Candida protocol, forget about that stuff you’re taking, it’s killing everything, and start putting in some things to grow back.
Jeff: And, not a single thing, and because they’re not our products I don’t mention them on air, but Matt, you can see that was there?
Matt: I mean you can use the Glutathione, you can use the G-Tox, you can use the Biogest, it’s just that other one that you’re putting in as an Antibacterial, it’s killing off the Bacteria and there’s nothing competing with the Candida. Most people get Candida overgrowth as a consequence of use of Antibiotics, and you’re using a Natural Antibiotic here right now long term, after shedding and stripping out a large population of your Natural Bacteria through the infection. So, it’s more about putting the Bacteria back in. What are you laughing at now?
Matt: Buckteria? You missed the Infucktion, I actually said, Fuckteria and Fucktion.
Jeff: You want to become a Kiwi don’t you because you want to be on the winning team.
Matt: Plus, South African, actually.
Jeff: No, that’s a Kiwi accent right there.
Matt: Oh, was it. Blowed if I know.
Jeff: Yeah, [01:11:42] mate, you want to be part of the All Blacks. I’ll get you a jumper.
Matt: I see you do the Haka almost every day when it’s time to pay for lunch, tapping all your different pockets, “Oh sorry, I’ve left my wallet behind.”
Jeff: Alright, Matt, anything else?
Matt: What’s a Hindu?
Jeff: [01:11:58]. Is that it?
Matt: Yeah, that’s my Kiwi joke, if that’s what you mean.
Jeff: It as alright. But no, for Alex.
Matt: Oh, Alex. Yeah, it depends who he goes for, really.
Matt: Follow up with this Alex and let us know if you’re an All Blacks supporter or a Wallabies supporter and that will determine what sort of diet I recommend, and whether you get any free product with it.
Jeff: Alex, I’ll get Elsa to send you out the Anti-Candida protocol, there’s none of our products…
Matt: AMP V.
Jeff: Oh the AMP V, alright.
Matt: Yeah, it gets rid of all the Bloating and swelling and that sort of stuff as well.
Jeff: There you go, Alex, you nearly missed out, AMP V, and then the Dorrigo Pepper and the one other one that you said.
Matt: I can’t remember that, but she’ll find them. Vietnamese Mint, eat heaps of that, it’s good, and buy Dorrigo Pepper which is an Australian mountain pepper.
Jeff: Cool. And that other hooroo…
Matt: Horopito, if you can find that.
Jeff: Horopito, okay.
Matt: There’s one product but they’ve changed it now, but there’s a company called Forest Herbs they make a product called Colarex, but the first one they made was the best and it was just Horopito, and when Horopito kills fungi it makes you fart, and so they give you the Aniseed to take with it to stop the farts.
Jeff: Wow, so maybe they should just come with a lump of charcoal.
Matt: Now, I think they just combine them together, but for some reason those original ones in the capsules in a box they worked so much better than these new soft gel caps they’ve got.
Jeff: That sucks when that happens.
Matt: Anyway, I will find some Horopito one day, and make an Anti-Candida product when we can.
Jeff: Mm, alright. Alex, best of luck, let us know how you get on.
Matt, that’s all we’ve got time for today. Last word?
Matt: Go Wallabies—please.
Jeff: And, on that high note we’ll leave it there.
Matt: It’s not as if they don’t try.
Jeff: Well, they brought back the Kiwi number 10.
Matt: Huh? Oh, don’t get me started on this. No, we shouldn’t talk about this.
Jeff: No, let’s leave it right there, let’s leave it on a happy high note.
Matt: Let’s just move on.
Jeff: Go All Blacks. See you guys.
Matt: No, no. Go Queensland.
Jeff: Alright, Hooroo.
END OF TRANSCRIPT